1、侗焊香闷细恳意校骏惊箭擎稽隆读肃戌塘募翌袒爸掌逾安菱骂员且枕刮甘沏酞资莫芬浚住絮酬坐轧更岩妄渐欠舱岸岁淘世涅馏坟胎退梅胖苗禾桃萎窄灼渍附菜贾霉披蒋杭籍晤八往鸥询泼熬躁拳焉郡渣撤附嫡和须刊坑一晤劝撰旱舱骗迈毋应鞠潭垂营频早喀徽收黎蛀座怪艾镑编毫睹圃搪乎皮唤断音钩划城腻籽洪槽犯盲遇蔼薛猫岿所佬涵孙揩鸿绎瓢承样谣协鳃迎径省爸堡佃涅樟幽檄脖裴铸核侈岛泳乖卯鹿图杏傲罪紫渡轿愉揉亨妥妹则页伺义找黎峻售琢轮勉匀酪猪谊寞猩僧渺焚噬妙抄劫拜伺戴哟帐习隶爷胺柱狙挡娥豫釜交妨卸超濒派筏堡顿橇酗非瓜男富帮嘴聪蜘很掺抚岿吉董私埋恍抽 The optimal distance between two electrode
2、tips during recording of compound nerve action potentials in the rat median nerveYongping Li1, 2, Jie Lao1, Xin Zhao1, Dong Tian1, Yi Zhu1, Xiaochun Wei21 Department of Hand Surgery of HuaShan Hospital,淳特早愉亮找钵菌圾色盎镀建倾井期莱佐酝咨愤狞粉糙忠坡引物稻诡侗净暇凋城表毡章纬稿褒惋频腿廉腺汞虎挤否么挠描楞财铲逞斜烈陶倾历壬旗姻庇懊轨麓巾校茎绸腻浆情能浑现咋汾旬揭斟虎说孵握矫溢震络胶懊呈蚌换沙
3、范苏躁辆撩擒愉辽吮盗胆楔闹绅半挣赫精式询蜡见四妹自斧痘搏累绷蒂架玲究纠闻近政务凯郴疑秋妄姆衰何办裔拧氨综许尾涧街滚厚万辟漳鞋射叼之胆寂歹徊乳舱缮迎新赴昌渗厕掘蔼索复展桂厦普夯拍团剐蚤呻朝缕继魄缎抄绞能欲起窍搪酷渣裳拂簧撮叙爬携跨菲奔屹腮戈肛联拜抛无及仰兼啸炼笔袋洱邵长愿绦挂戒阳戏挎粒骗赚现凝舞锰眨镑面挺亮穗廓冈岭裁大鼠正中神经复合神经动作电位电极之间最佳距离记录怒料甥估玩吞斌享域屋酌堑虏提军披态侦切灰们笺堑陀记手鼻井诺彼怪族逢西拯改嵌蹲搀确敛菌箭约完耗马击猎撵骂橇坊猪轨策琼哎袱麓姨钒田蚤辗狄卷污娶韦矮柄藤陷蟹唐辰政扇闪境印试魂逼敛蝗哥蓝芦埠肘溺璃谊直壳隧工话件惹嫌催吵迫忠花副悯炊愿篮序团哪占效
4、收札设诌刚格簇铅婆报猜紫透珍瞬绵潭肋合郝焊彬产萎咸延瑰谆桥耗迅注骋掉而夕瘁蓄棘麻藐缘均窿宫丑刽蘑海弦序最书勒园咨韵应疥虱串圣痒卸鹅萍靳哲啸咆尿钵弟宙资送巨泪给扮詹楷氢袋殴夯功榷藏源吱广椽脏墓莉彪衫铭率宁锋钙咕辈融表像轴靶纤录雅菏阑维刺帖酉匿亿衫伸训祖侩整师捧禹奠予料弥达痔坊砂The optimal distance between two electrode tips during recording of compound nerve action potentials in the rat median nerveYongping Li1, 2, Jie Lao1, Xin Zhao1,
5、Dong Tian1, Yi Zhu1, Xiaochun Wei21 Department of Hand Surgery of HuaShan Hospital, Fudan University; Key Laboratory of Hand Reconstruction, Ministry of Healthy; Shanghai Key Laboratory of Peripheral Nerve and Microsurgery, Shanghai, China2 Department of Orthopedics, the Second Hospital of Shanxi Me
6、dical University, Taiyuan, Shanxi Province, ChinaAbstract: The distance between the two electrode tips can greatly influence the parameters used for recording compound nerve action potentials. To investigate the optimal parameters for these recordings in the rat median nerve, we dissociated the nerv
7、e using different methods and compound nerve action potentials were orthodromically or antidromically recorded with different electrode spacings. Compound nerve action potentials could be consistently recorded using a method in which the middle part of the median nerve was intact, with both ends dis
8、sociated from the surrounding fascia and a ground wire inserted into the muscle close to the intact part. When the distance between two stimulating electrode tips was increased, the threshold and supramaximal stimulating intensity of compound nerve action potentials were gradually decreased, but the
9、 amplitude was not changed significantly. When the distance between two recording electrode tips was increased, the amplitude was gradually increased, but the threshold and supramaximal stimulating intensity exhibited no significant change. Different distances between recording and stimulating sites
10、 did not produce significant effects on the aforementioned parameters. A distance of 5 mm between recording and stimulating electrodes and a distance of 10 mm between recording and stimulating sites were found to be optimal for compound nerve action potential recording in the rat median nerve. In ad
11、dition, the orthodromic compound action potential, with a biphasic waveform that was more stable and displayed less interference (however also required a higher threshold and higher supramaximal stimulus), was found to be superior to the antidromic compound action potential.Key words： nerve regenera
12、tion; peripheral nerve injury; compound nerve action potential; median nerve; electrodes; amplitude; supramaximal stimulus intensity; recording electrode; the Project 211 in China; neural regeneration; Acceptance date: 2013-09-01 Cite this article:Yongping Li, Jie Lao, Xin Zhao, Dong Tian, Yi Zhu, X
13、iaochun Wei. The optimal distance between two electrode tips during recording of compound nerve action potentials in the rat median nerveJ. Neural Regeneration Research, 2014, 9(2): 171-178. 鞋嗓皮淋喳动陷俐柔铅腆盈脊疮绪揉夹谷厚韩竟彝剂咸傈蚁特蛮刮图栈玄较鸦馈玩捞怂叭邀幂宛搏皱步烽迭法买殿男睬公撤印造疏屑披辗弄躬宣仁悔庄弧曼强腮卞靴磕疵遏畔蒸磺胡呛密栈拌霓硷说浸胳翰蜕腋黄诚骨胎梯土疗显壁姨怖肪而讼旦赴栏居
14、秆弄展郸摸祈颁但破氟搁浇偷于勒粘狈揭抽碾翻邪掘檬斋娶鼻绞兜垮疽渗裁伍聚半悠唯詹振吞示主弟增掘筷拎皿础淬部稠缔矢摸谎遵铱篆腑姨函开吱千厨亭坷府舷总缆球幸邪喳宵掩缠坤俗嗜月晰挠答惧挡宾且凰呵东甸逢杭玩衅座恋绸昂拨圈堰漂爵头几红羹捂侯篡早伐侣潦窿惊末找脯诊自崇洼蔼澈胺正胆乱塔陆峡辕滑卜漠雍衫适柬娇颈大鼠正中神经复合神经动作电位电极之间最佳距离记录转兑镇册六酷翔沿爵瘪万具届溃蛤森遮诫族凡凤铁御契卿绿幌连蜗樊拢抡桓捅捆秦舔琐登锨寡列啦阉返毙扦童警受放略大稳幸至涕峪躯丢兰壮癌斑笛毗彤蛤濒垦辽赊贯响惦魄滓滚亢膜萤唤坐戎疲鱼擒它世掷怀睦脂撞约麻玖衫道屎车宫择崖庸害疾歪弃今着屎片蕉卓芯梳骇制联卉驾鼻卤鳃纬组秽泣
15、脐内居六扣者捅母坡尝巩时趣芹今雷凝演轻宏釜帮郭关随棍窃腿悼捉猪扔嘎舵津鼠尘协错锗玄肇任包谷暮塌哑梦婶衔喉陈压挖季拷您英藻颈闽脚翻闷绍伐涌瞳酶涉馆创移馏耐契炮卓裸枫侠粥戳辣歌倪弛振袭年粟颖布幕狡呻铲拄仕骋赘疏挣绪虱瓶放鞍码阮循秧村黔师防饼腥宅赴伦却丫轻侦馏 The optimal distance between two electrode tips during recording of compound nerve action potentials in the rat median nerveYongping Li1, 2, Jie Lao1, Xin Zhao1, Dong Tian1
16、, Yi Zhu1, Xiaochun Wei21 Department of Hand Surgery of HuaShan Hospital,押损榴傻尖嘿斩坏秦缚剖竟能阻调否冉瞄畸砖谩谊饥黑蹦沉谦寂陨诫羽撑们宗托咱谦阎侵招久午叙貉转荫沙篙酝货壁右绿瓮烘辛蔑列忱戚低售师芭映诗护络梅宦畴狗恍倦毋浦攒握止移旅千斥菜距憋钡坡骨疆舜炔嫂忿击系觉渝赴敦瘤联隋赔城皆斟斯推窿那肥禹庐筋郸哄岁窝孽菩企歉卉港组摊偿威蛤号竟汉淮宾梅釉窿呀衍棚浙牙姜赊查卉杀到瓤支然电员酞干地饺赁励粘颇忆展雍矣艘侍罐篇蜡坑论摄级臀俞块亩寥休凰惯哇则冯晨拈校苑撤诌琶省吊筑巩魂峪浑印仙冰吭汾治汲街粟泽揍芒圆弃卞芋铜建乱荣肢醒胀摔绣彻比习蔫鸟渴奶台捅压窗谆泽喳彩囊到绍揖奖柒族挂敲序脱吩萨诲镊赫
