1、 ; ; ; ; ; , Tel:13958066993;E-mail: (HFMD) , 5 , 1 A16 71 2 , 3, 4-5 , 1 1.1 2016 1 2016 12 103 , 53 , 32 , 21 , 112 , , 14 , ; 50 , 31 , 19 , 110 , , 13 , , (P0.05) 1.2 : (1) 2010 6 : , , ; (2) 112 ; (3) : (1) ; (2) , 2 , , 5% 200m L , ; , 1 0.5g, 100150m L , 1 2 5 : (1) : 2m L, 15cm, 3000r/min, 1
2、0min, , 24h (2) : 2m L, 10min, , 24h , - - -6 (IL-6) : SPSS19.0 , / , , , t , P0.05) ; ( t=33.564 20.386, t=14.436 7.534, P0.05) ; TNF- IL-6 , ( t=13.341 19.846, t=6.782 9.181, P0.05) ; TNF- IL-6 (t=9.179 13.506, P0.05) 3 3 4 , 8 , , , , , IL-6 TNF- IL-6 , , , TNF- , , 9 , IL-6 TNF- , HFMD , 10 , 11
3、 , , CG MCC0313.1, , , , , , , , 12-13 , (P0.05) , ; (P0.05) , , 14 15-16 , CRP TNF- IL-6 , TNF- IL-6 , TNF- IL-6 (P0.05) , TNF- IL-6 , , , 1Yuan GP, Yang XT, Guo ZP, et al.Enterovirus infection status among family members of children with hand foot and mouth disease and healthy children in Baoshan
4、district of ShanghaiJ.Disease Surveillance, 2015, 30 (4) :277-279. 2 . J. , 2013, 8 (15) :127-128. 3Wen Ping G, Xian-Dan L, Yi-Ping C, et al.Fourteen types of co-circulating recombinant enterovirus were associated with hand, foot, and mouth disease in children from Wenzhou, ChinaJ.Journal of Clinica
5、l Virology, 2015, 70 (1) :29-38. 4 , . J. , 2016, 7 (23) :64-64. 5 , . J. , 2016, 10 (19) :168-168. 6 . (2010 ) J. , 2010, 30 (24) :1473-1475. 7 . ( ) S. : , 2002:259-261. 8 , , . 146 J. , 2016, 51 (5) :435-436. 9 . J. , 2015, 24 (19) :3870-3870. 10 . J. , 2016, 6 (3) :98-100. 11 , , , . J. , 2014, 20 (9) :231-236. 12 . C - J. , 2014, 26 (7) :809-811. 13 , . J. , 2017, 28 (2) :171-172. 14 , , , . J. , 2013, 34 (16) :2173-2174. 15 , , , . J. , 2015, 18 (11) :1795-1798. 16 . J. , 2016, 3 (13) :2535-2536.
