1、,Articular cartilage injury of the knee,li yan,General Information,Name :Lu x xMale18Yoccupation :acrobat,pain, swelling,immobility of right knee for 2msworsen 2ds,Chief Complaint,History of present illness,pain, immobility ,swelling of right knee for 2ms when taking exercise2 days ago,injuried when
2、 jumping,then the symptom became worsen,Other Medical History,past history：（-）personal history：（-）family history：（-）,Right knee: swelling Floating patella test : (+) McMurray sign : (+) Drawer test : (-),Physical Examination,Physical Examination,LameMuscle atrophy ROM:0-130,Imaging Examination,MRI,d
3、efect 2*2cm,Lab Examination,Urine RT Blood RT Liver function Renal function ECGAll above is normal,Diagnosis,Articular cartilage injury of the knee,Surgery,Osteochondral Transplant,Result,Discussion,Function of articular cartilage:Variable load-bearing through a range of motion in functional activit
4、iesReduce stress on the subchondral bone & minimise frictionAbsorbs load-forces up to 5x body weight,Discussion,Healing Response : PathophysiologyNo blood supply No lymphatic drainage No neural element No immunological recognition,Discussion,Discussion,Full-thickness articular cartilage injury is no
5、toriously difficult to be treated in the fields of orthopedics and sports medicine.,Discussion,Once destroyed, is not repairedRepair cartilage is mainly of type I collagen with poor wear characteristics,Discussion,Substitution Replacement:Osteochondral transplantsAutologous chondrocyte implantation,Discussion,Allogeneic bone and cartilage transplantation can offer a transparent cartilage with biological activity and biomechanical properties to repair full-thickness articular cartilage defects.,,Thank You !,
