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1、传染病传播模型综述张发1,2李璐2宣慧玉21.空军工程大学工程学院,西安710038;2.西安交通大学管理学院,西安7100491000-6788(2011)09-1736-09N949;R131A建立传染病传播模型是理解传染病流行机理,预测流行趋势,进行防控决策的基础.将传染病传播模型分为单一群体模型,复合群体模型和微观个体模型三类.单一群体模型从宏观角度刻画了集计量的变化,以经典的SIR为基础,在仓室设置、年龄结构、随机性、异质性等方面进行了扩展.复合群体模型将人群划分为多个子群体,子群体之间因人口流动而耦合,适合研究具有空间异质性的跨地区传播问题.微观个体模型的出发点是个体状态和行为,所

2、有个体形成接触网络.这类模型有理想网络和现实网络两个研究方向,理想网络关注接触网络特性对传染病传播动力学的影响,现实网络致力于揭示社会接触的实际特征,构建足够真实的模拟网络,研究传染病的传播.这三类模型各有特点,分别具有各自的适用领域,应根据研究目的和问题特点选择合适的建模方法.传染病模型;仓室;复合群体;接触网络;综述Survey of transmission models of infectious diseasesZHANG FaLI LuXUAN Hui-yu2010-01-14国家自然科学基金(70971106);中国博士后科学基金(20070421118)作者简介:张发(1970

3、-),男,副教授,博士后,研究方向复杂系统仿真,E-mail: ;李璐(1977-),男,博士后,研究方向管理系统仿真,E-mail: ;宣慧玉(1942-),女,教授,博士生导师,研究方向系统仿真,E-mail:.173717381739174017411 Grassly N C, Fraser C. Mathematical models of infectious disease transmissionJ. Nature Reviews Microbiology,2008, 6(6): 477-487.2 Keeling M J, Rohani P. Modeling Infectio

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38、auchemez S, et al. Strategies for containing an emerging influenza pandemic in Southeast AsiaJ. Nature, 2005, 437(7056): 209-214.72 Longini I M, Nizam A, Xu S F, et al. Containing pandemic influenza at the sourceJ. Science, 2005, 309(5737):1083-1087.传染病传播模型综述作者: 张发, 李璐, 宣慧玉, ZHANG Fa, LI Lu, XUAN Hu

39、i-yu作者单位: 张发,ZHANG Fa(空军工程大学工程学院,西安710038;西安交通大学管理学院,西安710049), 李璐,宣慧玉,LILu,XUAN Hui-yu(西安交通大学管理学院,西安,710049)刊名: 系统工程理论与实践英文刊名: Systems Engineering Theory Fraser C Mathematical models of infectious disease transmission 2008(06)2.Keeling M J;Rohani P Modeling Infectious Diseases in Humans and Animals

40、 20073.Anderson R M;May R M Infectious Diseases of Humans,Dynamics and Control 19924.Riley S Large-scale spatial-transmission models of infectious disease外文期刊 2007(1)5.Koopman J Modeling infection transmission 20046.Kermack W O;McKendrick A G Contributions to the mathematical theory of epidemics,par

41、t I外文期刊 19277.Castillo-Chavez C;Castillo-Garsow C W;Yakubu A A Mathematic models of isolation and quarantine外文期刊 2003(21)8.蔡全才 定量评价SARS干预措施效果的传播动力学模型期刊论文-中华流行病学杂志 2005(03)9.Riley S;Fraser C;Donnelly C A SARS in Hong Kong:Impact of public health transmission dynamics of the etiological agent ofinterv

42、entions 2003(20)10.Nu(n)o M;Chowell G;Gumel A B Assessing the role of basic control measures,antivirals and vaccine in curtailing pandemicinfluenza:Scenarios for the US,UK and the Netherlands 2007(14)11.Fraser C;Donnelly C A;Cauchemez S Pandemic potential of a strain of influenza A(H1N1):Early findi

43、ngs外文期刊 2009(5934)12.Hoppensteadt F Mathematical Theories of Populations:Demographics,Genetics and Epidemics 197513.Rouderfer V;Becker N Assessment of two-dose vaccination schedules:Availability or vaccination and catch-up外文期刊1995(01)14.McKendrick A G Applications of mathematics to medical problems

44、192615.Isham V Stochastic Models for Epidemics 200516.Nasell Stochastic models of some endemic infections外文期刊 2002(01)17.Lajmanovich A;Yorke J A A deterministic model for gonorrhea in a nonhomogeneous population 1976(3/4)18.Gonzalez M C;Hidalgo C A;Barabsi A L Understanding individual human mobility

45、 patterns外文期刊 2008(7196)19.Grenfell B;Harwood J (Meta)population dynamics of infectious disease 1997(10)20.Hanski I Metapopulation theory,its use and misuse外文期刊 2004(03)21.Wang W;Mulone G Threshold of disease transmission in a patch environment外文期刊 2003(01)22.Castillo-Chavez C;Yakubu A A Dispersal,d

46、isease and life-history evolution外文期刊 2001(01)23.Cross P C;Johnson P L F;Lloyd-Smith J O Utility of R-0 as a predictor of disease invasion in structured populations2007(13)24.Colizza V;Vespignani A Epidemic modeling in metapopulation systems with heterogeneous coupling pattern:Theory andsimulations外

47、文期刊 2008(03)25.Watts D J;Muhamad R;Medina D C Multiscale,resurgent epidemics in a hierarchical metapopulation model 2005(32)26.Colizza V;Barrat A;Barthlemy M The role of the airline transportation network in the prediction and predictability ofglobal epidemics外文期刊 2006(07)27.Hufnagel L;Brockmann D;G

48、eisel T Forecast and control of epidemics in a globalized world外文期刊 2004(42)28.Wallinga J;Edmunds W J;Kretzschmar M Perspective:Human contact patterns and the spread of airborne infectious diseases外文期刊 1999(09)29.Liljeros F;Edling C R;Amaral L A N Sexual networks:Implications for the transmission of sexually transmitted infections2003(02)30.Keeling M J The i

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