1、 2015 1 2 016 6 60 , , , 2 , 13.33% (4/30) (P0.05) , ; ; ; ; , , , , : , E-mail: (No:2017KY6880) Curative effect of lauromacrogol histoacryl sandwich injection combined with ligation in the treatment of esophageal and gastric varices CHENG Ming TANG Shi-wei WANG Jian-jun LOU Miao-zi ZHAO Jian-feng F
2、ANG Li-min JIN Hao Department of Gastroenterology, Guangfu Hospital of Zhejiang Jinhua; Abstract ObjectiveTo investigate the curative effect of lauromacrogol histoacryl sandwich injection combined with ligation in the treatment of esophageal and gastric varices.Methods60 patients with esophageal and
3、 gastric varices in our hospital from January 2015 to June 2016 were selected.According to the patient treatment order in time, the patients were randomly divided into the control group and the observation group.The patients in the control group were treated with tissue glue combined with ligation,
4、and the patients in the observation group were treated with lauromacrogol histoacryl sandwich injection combined with ligation.The clinical efficacy, quality of life and complications were compared between the two groups.ResultsThe success rate of hemostasis in the observation group was significantl
5、y higher than that in the control group group was significantly lower than that in the control .After treatment, the physical function, psychological function, social function and material life condition scores in two groups were significantly changed in an uptrend (P0.05) .ConclusionWith good clini
6、cal efficacy, lauromacrogol histoacryl sandwich injection combined with ligation in the treatment of esophageal and gastric varices effectively improves the quality of life with high safety. Keyword Lauromacrogol histoacryl; Sandwich injection; Ligation; Esophageal and gastric varices; (gastric vari
7、ces, GV) , , , 1-2 GV , 3 , , , , , 4 , 60 , GV , 1 1.1 2015 1 2016 6 GV 60 : (1) GV , 2009 5; (2) ; (3) : (1) ; (2) ; (3) , 60 , 30 : 19 , 11 , 2075 , : 20 , 10 , 2175 , 2 (P0.05) , , 1 1.2 OLYMPUS CLV260 : EVL , 5 ml, , :0.52ml, 5ml , cook , , , : , 2ml, 1 ml, 2ml, 1 2 1.3 (1) 2 (2011 ) : (1) : 72
8、h ; : 272 , 30g/L (2) : 72h6 (3) : 6 (2) 2 6 (GQOLI-74) , , , (3) 2 , 1.4 SPSS 18.0 , , t ; , P0.05) ; , 13.33% (4/30) (P0.05) , 4 2 2 (%) 3 2 4 2 3 GV , , , 6-7 , , , , , , , , 8-11 , 10% , , , , 90 , 12-14 , , , , , , , , 15 , , , , , , 16 , 96.66%, 80.00%, , , , , , , 17-18, , , , , , , , , , GV
9、, 1 , . J. , 2015, 21 (7) :673-679. 2 , , , . J. , 2017, 34 (1) :49-51. 3 , , , . J. , 2016, 24 (10) :786-789. 4 , . J. , 2015, 19 (12) :1894-1898. 5 . (2009 ) J. , 2010, 27 (1) :1-4. 6 , , , . J. , 2016, 33 (12) :784-786. 7 , , , . J. , 2015, 43 (1) :53-55. 8 , , . J. , 2017, 17 (3) :428-430. 9 , ,
10、 , . J. , 2016, 35 (3) :202-204. 10 , , , . J. , 2016, 23 (4) :262-266. 11 . J. , 2016, 13 (22) :65-68. 12 , , . J. , 2016, 33 (12) :2318-2321. 13 , . J. , 2014, 22 (2) :98-99. 14Chirapongsathorn S, Manatsathit W, Farrell A M, et al.Su1498Safety and Efficacy of Endoscopic Cyanoacrylate Injection in
11、the Management of Gastric Varices:A Systematic Review and Meta-AnalysisJ.Gastroenterology, 2016, 150 (4) :1111-1111. 15 , , , . J. , 2015, 6 (21) :131-132. 16 , , , . J. , 2017, 23 (2) :6-9. 17Bhat Y M, Weilert F F, Fredrick R T, et al.EUSguided treatment of gastric fundal varices with combined injection of coils and cyanoacrylate glue:a large U.S.experience over 6years (with video) .J.Gastrointestinal Endoscopy, 2016, 83 (6) :1164-1172. 18 , , , . J. , 2016, 39 (2) :128-129.