1、 : -1 (aquaporin-1, AQP-1) (platelet activating factor, PAF) : 92 , 46 , 3 , 1 2 ; , 1 , 500 mg , 1 , 2 4 , AQP-1 PAF : , (P0.05) , 1.2 1.2.1 6 , , , B C 1.2.2 7 : , , , : , , 1.3 CSOM 2065 1 , 1.4 1.5 : ( , H20010330) , 3 , 12 , ; ( , H20080334) , 1 , 500 mg, 1 h : , : 15 g, 12 g, 10 g, 9g, 9 g, 9
2、g, 12 g, 10 g, 12g, 12 g, 10 g, 10 g 1 , : 1 1.6 (1 k Hz 2 k Hz 4 k Hz 8 k Hz) , 8 , , (0 ) (1 ) (2 ) (4 ) -1 (aquaporin-1, AQP-1) (platelet activating factor, PAF) 1.7 8 : , , : , , : , , , : , , 30% = ( + + 1.8 SPSS 19.0 , , t , , P0.05 2 2.1 1 2.2 2 2.3 3 2.4 AQP-1 PAF AQP-1 PAF 4 1 2 3 4 AQP-1 P
3、AF 3 CSOM , , , , , , , , , , , 9 , , , , , , , , 10 , , , , , , , CSOM ; ; ; ; , , ; ; ; ; , , , , , , , , (P0.01) ; 4 , 90.48%, 74.19%, (P0.05) , AQP , 11 AQP-1 AQP , , 12, AQP-1 13 PAF , , 14-15 , AQP-1 , PAF (P0.01) AQP-1 PAF , , , AQP-1 PAF 1SILVOLA J, KIVEKAS I, POE D S.Ballon dilation of the
4、cartilaginous portion of the eustachian tubeJ.Otolaryngol Head Neck Surg, 2014, 151 (1) :125-130. 2 . 43 J. , 2016, 36 (12) :2193-2195. 3 , , , . J. , 2014, 29 (9) :1378-1379. 4 , . 45 J. , 2016, 36 (4) :663-664. 5 . J. , 2013, 28 (8) :1245-1246. 6 , . (2004, ) J. , 2004, 4 (3) :137-141. 7 . S. : ,
5、1994:214-215. 8 . ( ) M. : , 2002:329, 363. 9 , , , . J. , 2013, 19 (13) :311-314. 10 , . J. , 2014, 12 (9) :26-27. 11SEO Y J, CHOI J Y.Expression and Localization of Aquaporin Water Channels in Human Middle Ear EpitheliumJ.Otol Neurotol, 2015, 36 (7) :1284-1289. 12 , , . 1 J. , 2015, 44 (6) :731-732. 13 , , , . 1 4 J. , 2016, 22 (12) :191-194. 14 , , , . PAF, ET-1 J. , 2016, 22 (10) :158-161. 15 , , . J. , 2016, 24 (3) :232-234.
