1、肥胖基因与脉冲控制Dr. Cindy Haines2014 年 5 月 27 日为什么有些人随着年龄的增长会肥胖，有些人却不会？生物学和行为可能是组合键。Why do some people pack on the pounds as they grow older while others dont? Biology and behavior may be the key combo.新的研究表明携带一种特殊形式肥胖基因的人随着年龄的增长面临较高的脉冲控制的丧失的风险。该基因变异也似乎促进对高热量食物的需求的增长。New research shows people who carry a p
2、articular form of the so-called obesity gene face a higher risk for losing impulse control as they age. The gene variant also seems to promote an increased desire for high-calorie foods. 为了探讨它在肥胖风险中的作用，研究人员对约 700 名携带这种基因变异的受试者进行了脑部扫描。通过分析发现，随着具有该基因变异的人老龄化，基因变异与身体质量指数增加之间的相关性与先前的研究相一致。还发现，在他们的大脑内侧前额叶
3、皮质区活动下降。该区域被认为负责响应食物的味道和本质，并控制脉冲反应。To explore the role it plays in obesity risk, investigators conducted brain scans on nearly 700 participants who carried the gene variant. The analysis revealed that as people with the variant got older, the association between the gene variant and increasing body
4、mass index remained consistent with earlier research. They also found that activity in the medial prefrontal cortex region of their brains fell. Thats the area that is thought to respond to the taste and texture of food and to control impulses. 研究人员说，这些发现揭示了一个复杂的路径即肥胖基因可通过改变中老年人的生活行为如更多的脉冲活动和对热量丰富的食物的偏爱导致体重增加。The researchers say these findings uncover a complex pathway through which the obesity gene may induce weight gain through changes in behavior in middle and late life, such as greater impulsivity and a preference for calorie-rich foods.
