1、-levofloxacin hydrochloride and sodium chloride injectionyansuan zuoyangfushaxing lhuana zhusheye(s)-(-)-9-23-3-10-(4-1-)-7-7h-123-de-14f-6-c18h20fn3o4hclh2o415.85cas no177325-13-2-:():():() :()2ml:0.1g() 400ml(0.4g)2-(-)600ml(0.6g)2-0.1%5%-181. 604.-(0.1%)1. 2. -() -:-()got/gpt/al-p/-(1)():(2):(3):
2、(4):dna()-dna-:-ld50:1.881mg/kg1.478mg/kg250mg/kg :-450200mg/kg800mg/kgm/e-41030mg/kg100mg/kgph:-2620mg/kg80320mg/kgph320mg/kg-26102562.5mg/kg:-360mg/kg:-90mg/kg-50mg/kg:-360mg/kg:(34)(4)-7300mg/kg10mg/kg(13)-740mg/kg18(14)30mg/kg:(320400nm)-200mg/kg300mg() 300mg(n=8)(n=12)(300mg6)24485.356.12g/ml-4
3、8-87%724%5%(capd)2018-levofloxacin and sodium chloride injectionzuoyangfushaxing lvhuana zhusheyeph (s)-9-2,3-3-10-(4-1-)-7-7h-1,2,3-de-1,4-6-:c18h20fn3o41/2h2o:370.38cas no100986-85-4,-1234567100ml:0.5g0.9g:100ml:0.5g,0.5g(1),1-0.1%5%-181. 100ml602. 50ml/2050ml/ 0.5g240.25g1019ml/ 0.5g240.125g10ml/
4、 0.5g240.125g3. -4. -(0.1%)12-1. 2. -3. -4. 5. -got/gpt/al-p/-1231. dnaii-dna-2. 1-ld50:1,881mg/kg,1,478mg/kg250mg/kg2-450mg/kg200mg/kg800mg/kgm/e-410mg/kg30mg/kg100mg/kgph(3)-2620mg/kg80mg/kg320mg/kgph320mg/kg-2610mg/kg25mg/kg62.5mg/kg(4)-360mg/kg(5)-90mg/kg-50mg/kg(6)-360mg/kg(7)344-7300mg/kg10mg/kg13-740mg/kg181430mg/kg8320400nm,-200mg/kg0.5g,t1/268,7024clt1/2capd)3623-23-2368750mg250500mg4040046-auc/miccmax/miccmax/mic12.299auc/mic100550auc/mic100