1、This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller
2、and DS18B20 temperature sensor.多发性骨髓瘤的诊治This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of
3、 the system are AT89C51 microcontroller and DS18B20 temperature sensor.基本概念定义 多发性骨髓瘤（ multiple myeloma, MM）是浆细胞异常增殖的恶性肿瘤。其特征为 浆细胞异常增生并分泌单克隆免疫球蛋白或其片段（ 即 M蛋白） ，并 导致相关器官或组织损伤 。流行病学约占全部恶性肿瘤的 1%，血液系统恶性肿瘤的 10%。我国中位发病年龄 57岁，发病高峰 5060岁，男性多于女性。This paper mainly introduces the design of an intelligent tempera
4、ture control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.病因和发病机制MM病因和 发病机制目前尚不明确 ，研究发现下列因素可
5、能与其发病有关电离辐射慢性抗原刺激遗传因素病毒感染（ EB病毒、 HHV-8）基因突变This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components
6、 of the system are AT89C51 microcontroller and DS18B20 temperature sensor.病理生理和临床表现骨髓瘤细胞恶性增生并广泛浸润，以及单抗隆免疫球蛋白 产生一系列相关的临床症状骨痛，腰骶部 最多见，其次 胸肋部 ；高钙血症贫血及出血倾向；高粘滞综合征蛋白尿、本 -周蛋白尿、血尿，肾功能不全 ，管型肾病易 致 感染，肺炎链球菌性肺炎最常见，其次泌尿系感染和败血症This paper mainly introduces the design of an intelligent temperature control system w
7、hich realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor. 骨骼破坏骨痛病理性骨折串珠样结节贫血孤立性骨髓瘤This paper mainly introduces t
8、he design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor
9、.This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller
10、 and DS18B20 temperature sensor.器官肿大（肝脾淋巴结）神经损害（截瘫， POEMS综合征 ）髓外骨髓瘤浆细胞白血病 髓外浸润This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip
11、 microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature
12、 sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using
13、 single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.原因是游离轻链、高钙血症、高尿酸血症第二位的死亡原因This paper mainly introduces the design of an intelligent temperature control system which realizes the
14、 function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.This paper mainly introduces the design of an intelligent temperature co
15、ntrol system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.This paper mainly introduces the design o
16、f an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.This paper
17、 mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B2
18、0 temperature sensor.This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT8
19、9C51 microcontroller and DS18B20 temperature sensor.实验室检验及影像检查This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer.
20、The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.实验室检验及影像检查（一）血常规多为正细胞正色素性贫血，可有大细胞性贫血伴骨髓幼红细胞类巨幼变 ，营养不良时可表现为小细胞低色素性贫血。 白细胞、血小板正常或偏低 。并可发现骨髓瘤细胞在血中大量出现，超过 2X109/L者，称为浆细胞白血病。外周血涂片示红细胞呈 “ 缗钱状 ” 排列This paper mainly introduces the design of an intelligent tempera
21、ture control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.实验室检验及影像检查（二）骨髓象骨髓增生活跃，浆细胞 异常增殖，占
22、1095%，红系、粒系不同程度的受到抑制。由于骨髓瘤细胞早期常为灶性分布，当诊断有怀疑时，应当做多部位特别是疼痛部位的骨髓穿刺。This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer
23、. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor. 骨髓检查： 骨髓活检免疫组化 （骨髓免疫组化建议应包括抗体：CD5、 CD19、 CD23、 CD25、 CD20、 CD38、 CD56、 CD138、 、 ） 流式细胞术 （建议至少包括的免疫标记： CD45、 CD138、 CD38、 CD56、 CD19、 、 ，有条件者可增加 CD28、CD27、 CD117、 CD81、 CD200)荧光原位杂交技术 建议 CD138分选骨髓瘤细胞或同时行胞浆
24、免疫球蛋白染色以区别浆细胞，检测位点建议包括： IgH重排、 17p-（ P53缺失）、 13q14缺失、 lq21扩增；若 FlsH检测 IgH重排阳性，则进一步检测 t(4;14）、t(11;14）、 t(14;16）、 t(14;20）等 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digit
25、al temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.VHCH1VHCH1CH2CH1CH1CH2VLCLVLCLS-SS-SM蛋白有三种类型：免疫球蛋白分子游离 的 轻链某种重链的片段免疫球蛋白的结构模式图免疫球蛋白的结构模式图实验室检验及影像检查（三）This paper mainly introduces the design of an
26、 intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.分分 型型 IgG型IgA型
27、IgD型IgM型IgE型轻链型双克隆型不分泌型 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are
28、AT89C51 microcontroller and DS18B20 temperature sensor.多发性骨髓瘤分型重链： 链 IgG型 链 IgA型 链 IgM型 链 IgD型 链 IgE型轻链： This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sen
29、sor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.血浆 M蛋白检测1、血清蛋白电泳表现为“ 窄底高峰 ” 的异常单克隆条带（及 M蛋白）。2、血清免疫固定电泳表现为异常沉淀弧，可确定单克隆免疫球蛋白类型，从而对 MM进行分型。This paper mainly introduces the design of an intelligent temperature contro
30、l system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.IgG- 型IgG- 型IgA- 型 IgM- 型This paper mainly in
31、troduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperat
32、ure sensor.实验室检验及影像检查（四）尿 M蛋白检测24h尿蛋白定量 ：多表现为大量蛋白尿，常与尿常规蛋白定性结果不符。尿 本周 蛋白电泳 和尿 免疫固定电泳 ：可进一步证实M蛋白的存在。This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS
33、18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.实验室检验及影像检查（五）NCCN专家组推荐 ：初始诊断中的骨髓检查应包括对骨髓穿刺所取浆细胞进行常规染色体核型分析（细胞遗传学）和荧光原位杂交检测（ FISH）。MM已确定的特殊的染色体异常包括异位、缺失或扩增。提示不良预后的染色体异常 ： 13号染色体缺失 ，17p13缺失 ， 14q32易位 亚型 t（ 4； 14） （ p16；
34、q32）和 t（ 14； 16）（ q32； q23） ， 1q21的获取 /扩增 。This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components
35、 of the system are AT89C51 microcontroller and DS18B20 temperature sensor.实验室检验及影像检查（六）其它实验室检验免疫球蛋白定量检查血液轻链、重链检查肾功能： SCr、 BUN、 UA肝功能：球蛋白 ，白蛋白 电解质：血 Ca血乳酸脱氢酶 ： 评估肿瘤细胞负荷血沉 、 C反应蛋白 血 2-MG ： 判断预后和疗效的重要指标This paper mainly introduces the design of an intelligent temperature control system which realizes t
36、he function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.实验室检验及影像检查（七）影像学检查X射片可见 弥散性骨质疏松、圆形或卵圆形穿凿样溶骨性病变、病理性骨折。This paper mainly
37、 introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 tempe
38、rature sensor.实验室检验及影像检查（八） X线射片是最传统的评估骨髓累及范围及程度的方法，但灵敏性较差，只有骨脱 Ca超过 30%以上时才能检测到溶骨性改变。 MRI、 CT、 PET-CT检查较灵敏，特别是当瘤细胞侵犯到椎体、骨盆、神经系统时，对定位诊断有较高的价值， IMWG 将 MRI视为 MM骨髓侵犯的影像金标准 。 全身 核素 骨 显像可见异常放射性核素浓集区 ，灵敏度较高，但特异性差，指南不推荐作为 MM常规诊断项目。This paper mainly introduces the design of an intelligent temperature contro
39、l system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.中国症状性 MM的诊断标准（ 2014诊疗指南）诊断和鉴别诊断（一）This paper
40、mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.诊断和鉴别诊断（一）
