1、张岳TomoTherapy介绍15,Aug,2010张岳, M.Sc, certified medical physicistTomoTherapy IncorporatedCO 6019551972Clinac 41988EPID MLC1995Serial tomotherapy(1st commercial IMRT)2001IMRT2003CT Guided IG-IMRT(TomoTherapy)2008RapidArcIMAT放 史 疗历 C-臂型机架19923D Treatment19961968(commercialized versions) 1983MRI1992Helic
2、al CT 1995Helical Multi slice CT 2002PET/CT usecommonIn RT 影像 滑 机架 特征设备 环 为2005CBCT品商 化产 业Helical TomoTherapy2003C-Arms inventedfor diagnostic X-RaysEarly 1900s TomoTherapy 是从CT机演 而来 变 (滑 式机架环 ) C-臂加速器来自传统X-光机的设计 TomoTherapy就是 为 IG-IMRT而 生的诞2005AdaptivePlanningDGRTDose Verification2007StatRTThroughp
3、ut and Reliability Enhancements20082003CT外照射放疗的历史演变Hi-Art 的构造Front view 6MV linear acceleratorCT detectorBeam stopMagnetronSSMHV power supplyMLC以螺旋CT 方式扫描和治疗癌症Courtesy, Dirk Verellen, VUB Hospital, Brussels 能够一次完成调强治疗的范围是40厘米直径X160厘米长 等中心和治疗床的精度都达到0.1 毫米 3 mmError 5 mmError 10 mm一 一次不 一次Adapted from
4、 Zeidan et al, Int. J. Radiat. Oncol. Biol. Phys. 2007; 67:670-677头 的 Copyright 2008 TomoTherapy Incorporated. All Rights Reserved.Click to edit Master title style Click to edit Master text styles Second level Third level Fourth level Fifth level26Density Plugs +3% Contrast-6% ContrastWaterTomo 和 CB
5、CT的图像TomoTherapyKVCB1 cGyUW Madison Tomotherapy Unit5 cGyCopyright 2008 TomoTherapy Incorporated. All Rights Reserved.Click to edit Master title style Click to edit Master text styles Second level Third level Fourth level Fifth level27Images Courtesy ofM.D. Anderson - Orlando Planning kV CTTomoMVCTM
6、VCT ImagesNo high-Z artifactProstate visibilityMVCT在 金 物对 属 质成像上几乎无 影伪Copyright 2008 TomoTherapy Incorporated. All Rights Reserved.Click to edit Master title style Click to edit Master text styles Second level Third level Fourth level Fifth level28The imaging dose depends on object size, beam collimation, filtration of the x-ray source, etc.28IGRT 影像系统成像剂量TomoTherapy影像 调强(IG/IMRT)治疗fi床