1、 MHD UP : (MHD) (UP) , , - - : 90 (CKD5 ) , MHDUP 3 : , , , , 30 3 , (VAS) PTH C (hs-CRP) - - -6 (IL-6) : : (P0.05) , VAS PTH (hs-CRP TNF- IL-6) (P0.05) , : MHDUP PTH , MHDUP - - ; ; ; ; ; , , : E-mail:ha- (YB2015162) (UP) (MHD) , , , , 1, UP , H1 , , 2, , , , , UP PTH , , 3, PTH , UP , , , , , , ,
2、, , , 4 , UP , PTH , UP , - - , , , , 1 1.1 , CKD5 UP , , 05 , 30 17 , 13 , 4058 , , (Body Mass In- 17 , 6 , 7 ; 19 , 11 , 4260 , , (50 13 , 8 , 9 ; 26 , 14 , 4262 , , 15 , 9 , 6 3 , 1.2 1.2.1 K/DOQI , 5 5, e 1.2.2 6 : : , , , ; : , , , , , , 3 ( ) 2 ( ) + 3 1.3 1.3.1 ; 4065 ; ; 1.3.2 ; , ; ; ; ; 1.
3、4 K/DOQI , ( ) ; , 10mg, qd, 30d, , H20070030; , : 30g 20g 10g 20g 10g 15g 30g, , 200ml , , , 30d, , 1.5 1.5.1 (VAS) 10 , 10cm , 0 , ;10 , 7 1.5.2 TNF- hs-CRP IL-6 3-4ml , 4000 rpm 10min, - , ELISA , , 1.5.3 , 7: (1) : , 1 (2) : , (3) : (4) : 1.6 SPSS18.0 , , t , ; t , P0.05 2 (P0.05) , 1 1 (n=30) 3
4、 VAS PTH (hs-CRP TNF- IL-6) (P0.05 P0.01) ; , VAS PTH (hsCRP TNF- IL-6) (P0.05) 1-3 2 VAS PTH 3 3 , , , , A 8-9 , MHD UP PTH , PTH , 10, , 11-12 , , , , MHD UP, , , -PTH , 13 , , , , , PTH , -PTH , , , - - , , , , , , , , , , , , , 14 , , , MHD UP , - - , , , , MHD UP - - , 1Mistik S, Utas S, Ferahb
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6、M, et al.Uremic pruritus:a clinical study of maintenance hemodialysis patientsJ.J Dermatol, 2002, 29 (10) :621-627. 8 . M. : , 1992:167-168. 9Mettang T, Kremer AE.Uremic pruritusJ.Kidney Int, 2015, 87 (4) :685-691. 10 , , , . J. , 2011, 12 (7) :637-638. 11 , . J. , 2009, 32 (6) :7-10. 12 , , , . J. , 2007, 6 (3) :171-173. 13 , . 4 J. , 2012, 15 (1) :25. 14 , , , . J. , 2005, 18 (5) :517-519.
