1、This paper mainly int roduces the design of an inteligent emperature cont rol system which realizes the function of temper at ur e measurement and cont rol by using single bus digit al temperature sensor DS18B20 and single chip microcom puter. The core component s of the system ar e AT89C51 micr oco
2、ntroler and DS18B20 t emperature sensor. 老年女性冠心病特点 解放军总医院心内科 董蔚 This paper mainly int roduces the design of an inteligent emperature cont rol system which realizes the function of temper at ur e measurement and cont rol by using single bus digit al temperature sensor DS18B20 and single chip microcom
3、 puter. The core component s of the system ar e AT89C51 micr ocontroler and DS18B20 t emperature sensor. 步调一致？ 2 略有不同？ This paper mainly int roduces the design of an inteligent emperature cont rol system which realizes the function of temper at ur e measurement and cont rol by using single bus digit
4、 al temperature sensor DS18B20 and single chip microcom puter. The core component s of the system ar e AT89C51 micr ocontroler and DS18B20 t emperature sensor. 流行病学 发达国家最常见死因，发病率及流行显著下降 美国每年近 1百万的心血管死亡人数的一半以上为女性 This paper mainly int roduces the design of an inteligent emperature cont rol system whi
5、ch realizes the function of temper at ur e measurement and cont rol by using single bus digit al temperature sensor DS18B20 and single chip microcom puter. The core component s of the system ar e AT89C51 micr ocontroler and DS18B20 t emperature sensor. 流行病学 2007 年欧洲心脏年会发布的最新资料表明 ,女性心血管病死亡率显著高于男性：女性心
6、血管病死亡率为 55% ,男性为 43% 慢性冠心病在老年女性中更加普遍 欧洲女性心血管病死亡率的增加主要与老年女性心肌梗死的增加有关。 This paper mainly int roduces the design of an inteligent emperature cont rol system which realizes the function of temper at ur e measurement and cont rol by using single bus digit al temperature sensor DS18B20 and single chip mic
7、rocom puter. The core component s of the system ar e AT89C51 micr ocontroler and DS18B20 t emperature sensor. 中 国 女性心血管死亡占所有死亡的 40.83% 大约是恶性肿瘤的 2倍 心血管疾病成为 40岁以上女性死亡的首因 认识、诊断、治疗 不当 女性患者和临床医师 缺乏识别，积极措施少 This paper mainly int roduces the design of an inteligent emperature cont rol system which realizes
8、 the function of temper at ur e measurement and cont rol by using single bus digit al temperature sensor DS18B20 and single chip microcom puter. The core component s of the system ar e AT89C51 micr ocontroler and DS18B20 t emperature sensor. 中 国 This paper mainly int roduces the design of an intelig
9、ent emperature cont rol system which realizes the function of temper at ur e measurement and cont rol by using single bus digit al temperature sensor DS18B20 and single chip microcom puter. The core component s of the system ar e AT89C51 micr ocontroler and DS18B20 t emperature sensor. 国内对心血管病死亡的预测结
10、果显示 由于人口老龄化和危险因素水平的增加 , 2010 年北京地区大约有 9390 人死于冠心病，男性 5565 人 ,女性 3825 人 男性冠心病死亡增加 24. 2 %,女性冠心病死亡增加31. 0 % 男性冠心病死亡人数多于女性 ,但女性冠心病死亡增加明显高于男性 ,即女性有明显的上升趋势。 This paper mainly int roduces the design of an inteligent emperature cont rol system which realizes the function of temper at ur e measurement and c
11、ont rol by using single bus digit al temperature sensor DS18B20 and single chip microcom puter. The core component s of the system ar e AT89C51 micr ocontroler and DS18B20 t emperature sensor. 绝经与冠心病 平均绝经年龄 51岁 在 50岁时 , 发展为 CVD的危险 39% CVD和癌症是目前最主要的致死病因 This paper mainly int roduces the design of an
12、inteligent emperature cont rol system which realizes the function of temper at ur e measurement and cont rol by using single bus digit al temperature sensor DS18B20 and single chip microcom puter. The core component s of the system ar e AT89C51 micr ocontroler and DS18B20 t emperature sensor. 佛莱明翰关于
13、女性心血管疾病 10年危险度的评分 This paper mainly int roduces the design of an inteligent emperature cont rol system which realizes the function of temper at ur e measurement and cont rol by using single bus digit al temperature sensor DS18B20 and single chip microcom puter. The core component s of the system ar
14、e AT89C51 micr ocontroler and DS18B20 t emperature sensor. AHA/ACC2010 女性心血管疾病的危险分层 危险等级 标准 高危（ 1个高危因素） 有临床表现的冠状动脉性心脏病 有临床表现的脑血管疾病 有临床表现的外周血管疾病 腹主动脉瘤 终末期或慢性肾脏疾病 糖尿病 10年心血管疾病的预测风险 10% 危险（ 1个主要危险因素） 吸烟 收缩压 120mm Hg，舒张压 80mm Hg 或治疗的高血压 总胆固醇 200mg/dl, HDL-C 50 mg/dl,或治疗的血脂异常 肥胖， 特别是向心性肥胖 饮食不当 缺乏体育锻炼 过早患
15、有心血管疾病的家族史（直系亲属 男性 55岁 女 性 65岁 代谢综合症 进展性亚临床性动脉粥样硬化（比如 冠状动脉钙化 颈动脉斑块 或 增厚的内膜 ) 踏车试验中较差的运动耐量或停止运动后心率恢复不正常 系统性自身免疫性胶原 -血管性疾病 (比如红斑狼疮或类风 湿性关节炎 ) 理想的心血管健康（包括以下项目） 总胆固醇 200mg/dl,（未治疗） 血压 120/80 mm Hg（未治疗） 空腹血糖 100mg/dl,（未治疗） 体重指数 25kg/ m2 戒烟 20岁成年人的体育锻炼 中等强度 150分钟 /周 剧烈强度 75分钟 /周，或综合健康饮食 (预防高血 压 的饮食方式 ) Th
16、is paper mainly int roduces the design of an inteligent emperature cont rol system which realizes the function of temper at ur e measurement and cont rol by using single bus digit al temperature sensor DS18B20 and single chip microcom puter. The core component s of the system ar e AT89C51 micr ocont
17、roler and DS18B20 t emperature sensor. 不同年龄组的女性冠心 病症状表现不同 围绝经期妇女 , 主诉多 , 恐惧心脏发生严重问题。 其中焦虑、抑郁占 20% 。 冠状动脉造影检查未发现严重的血管狭窄。 70岁以上的老年妇女 患有代谢综合征或者并发糖尿病 症状、心电图不典型 冠状动脉造影显示多支狭窄病变 ,甚至失去了有效的治疗机会。 This paper mainly int roduces the design of an inteligent emperature cont rol system which realizes the function o
18、f temper at ur e measurement and cont rol by using single bus digit al temperature sensor DS18B20 and single chip microcom puter. The core component s of the system ar e AT89C51 micr ocontroler and DS18B20 t emperature sensor. 辅助检查对女性冠心病的诊断价值 负荷超声心动图及负荷心肌核素的敏感性及特异性好于平板运动试验 This paper mainly int rodu
19、ces the design of an inteligent emperature cont rol system which realizes the function of temper at ur e measurement and cont rol by using single bus digit al temperature sensor DS18B20 and single chip microcom puter. The core component s of the system ar e AT89C51 micr ocontroler and DS18B20 t empe
20、rature sensor. 急性冠脉综合症的男女差异（ The GUARANTEE Registry） 入选 2,948 例患者， 1,160例 (39%) 为女性 13 (Am J Cardiol 1999;84:11451150) 平均年龄女性大 高血压更多 糖尿病更多 既往有心肌梗死、心力衰竭更多 This paper mainly int roduces the design of an inteligent emperature cont rol system which realizes the function of temper at ur e measurement and
21、 cont rol by using single bus digit al temperature sensor DS18B20 and single chip microcom puter. The core component s of the system ar e AT89C51 micr ocontroler and DS18B20 t emperature sensor. 年龄及性别对急性心肌梗死院内死亡率的影响 This paper mainly int roduces the design of an inteligent emperature cont rol system
22、 which realizes the function of temper at ur e measurement and cont rol by using single bus digit al temperature sensor DS18B20 and single chip microcom puter. The core component s of the system ar e AT89C51 micr ocontroler and DS18B20 t emperature sensor. 女性冠心病患者部分临床特征 较男性晚出现冠心病临床表现 10-20年 核素或超声心动图
23、可提高运动试验的诊断准确性 女性更易有不典型心肌梗死症状：呼吸困难，腹、颈及肩部疼痛。 女性较男性 MI死亡率及再梗死率高 15 N.K. Wenger / Cardiovascular Research 53 (2002) 558 567 This paper mainly int roduces the design of an inteligent emperature cont rol system which realizes the function of temper at ur e measurement and cont rol by using single bus dig
24、it al temperature sensor DS18B20 and single chip microcom puter. The core component s of the system ar e AT89C51 micr ocontroler and DS18B20 t emperature sensor. 女性冠心病患者治疗 抗血小板及抗凝治疗 他汀类药物的应用 冠状动脉介入治疗 做好预防工作 This paper mainly int roduces the design of an inteligent emperature cont rol system which re
25、alizes the function of temper at ur e measurement and cont rol by using single bus digit al temperature sensor DS18B20 and single chip microcom puter. The core component s of the system ar e AT89C51 micr ocontroler and DS18B20 t emperature sensor. AHA/ACC2010 女性心血管疾病的危险分层 危险等级 标准 高危（ 1个高危因素） 有临床表现的冠
26、状动脉性心脏病 有临床表现的脑血管疾病 有临床表现的外周血管疾病 腹主动脉瘤 终末期或慢性肾脏疾病 糖尿病 10年心血管疾病的预测风险 10% 危险（ 1个主要危险因素） 吸烟 收缩压 120mm Hg，舒张压 80mm Hg 或治疗的高血压 总胆固醇 200mg/dl, HDL-C 50 mg/dl,或治疗的血脂异常 肥胖， 特别是向心性肥胖 饮食不当 缺乏体育锻炼 过早患有心血管疾病的家族史（直系亲属 男性 55岁 女 性 65岁 代谢综合症 进展性亚临床性动脉粥样硬化（比如 冠状动脉钙化 颈动脉斑块 或 增厚的内膜 ) 踏车试验中较差的运动耐量或停止运动后心率恢复不正常 系统性自身免疫性
27、胶原 -血管性疾病 (比如红斑狼疮或类风 湿性关节炎 ) 理想的心血管健康（包括以下项目） 总胆固醇 200mg/dl,（未治疗） 血压 120/80 mm Hg（未治疗） 空腹血糖 100mg/dl,（未治疗） 体重指数 25kg/ m2 戒烟 20岁成年人的体育锻炼 中等强度 150分钟 /周 剧烈强度 75分钟 /周，或综合健康饮食 (预防高血 压 的饮食方式 ) This paper mainly int roduces the design of an inteligent emperature cont rol system which realizes the function
28、of temper at ur e measurement and cont rol by using single bus digit al temperature sensor DS18B20 and single chip microcom puter. The core component s of the system ar e AT89C51 micr ocontroler and DS18B20 t emperature sensor. 指南对于阿司匹林一级预防的建议 18 阿司匹林 低危 根据目前的临床试验的结果，不推荐在低危女性常规应用阿司匹林（ III,B） This pa
29、per mainly int roduces the design of an inteligent emperature cont rol system which realizes the function of temper at ur e measurement and cont rol by using single bus digit al temperature sensor DS18B20 and single chip microcom puter. The core component s of the system ar e AT89C51 micr ocontroler
30、 and DS18B20 t emperature sensor. 抗血小板药物在急性冠脉综合症中的应用 - 不稳定性心绞痛治疗的男女差异（ The GUARANTEE Registry） 19 (Am J Cardiol 1999;84:11451150) 用药情况：抗栓及抗凝药物的应用男性与女性之间存在较大差别 This paper mainly int roduces the design of an inteligent emperature cont rol system which realizes the function of temper at ur e measuremen
31、t and cont rol by using single bus digit al temperature sensor DS18B20 and single chip microcom puter. The core component s of the system ar e AT89C51 micr ocontroler and DS18B20 t emperature sensor. 氯吡格雷在女性及男性应用中的相对获益及安全性 20 共计 5个随机对照试验， 79613例患者，其中女性 23522例，占30%（ 20%-39%）。 (J Am Coll Cardiol 2009;
32、54:193545) This paper mainly int roduces the design of an inteligent emperature cont rol system which realizes the function of temper at ur e measurement and cont rol by using single bus digit al temperature sensor DS18B20 and single chip microcom puter. The core component s of the system ar e AT89C
33、51 micr ocontroler and DS18B20 t emperature sensor. 氯吡格雷在女性及男性应用中的相对获益及安全性 21 (J Am Coll Cardiol 2009;54:193545) This paper mainly int roduces the design of an inteligent emperature cont rol system which realizes the function of temper at ur e measurement and cont rol by using single bus digit al te
34、mperature sensor DS18B20 and single chip microcom puter. The core component s of the system ar e AT89C51 micr ocontroler and DS18B20 t emperature sensor. 氯吡格雷在女性及男性应用中的相对获益及安全性 22 (J Am Coll Cardiol 2009;54:193545) 女性较男性基线情况差异 ：年龄大，危险因素多，接受CABG及 PCI少，联合应用阿司匹林少 This paper mainly int roduces the desig
35、n of an inteligent emperature cont rol system which realizes the function of temper at ur e measurement and cont rol by using single bus digit al temperature sensor DS18B20 and single chip microcom puter. The core component s of the system ar e AT89C51 micr ocontroler and DS18B20 t emperature sensor
36、. 氯吡格雷在女性及男性应用中的相对获益及安全性 23 (J Am Coll Cardiol 2009;54:193545) 主要心血管事件 ：男性 OR下降 16%，有统计学差异，女性仅下降7%，但男性与女性之间差异无统计学意义（ p=0.092） This paper mainly int roduces the design of an inteligent emperature cont rol system which realizes the function of temper at ur e measurement and cont rol by using single bu
37、s digit al temperature sensor DS18B20 and single chip microcom puter. The core component s of the system ar e AT89C51 micr ocontroler and DS18B20 t emperature sensor. 氯吡格雷在女性及男性应用中的相对获益及安全性 24 (J Am Coll Cardiol 2009;54:193545) 全因死亡 ：男性 OR下降 9%，有统计学差异，女性仅下降 1%，但男性与女性之间差异无统计学意义（ p=0.158） This paper m
38、ainly int roduces the design of an inteligent emperature cont rol system which realizes the function of temper at ur e measurement and cont rol by using single bus digit al temperature sensor DS18B20 and single chip microcom puter. The core component s of the system ar e AT89C51 micr ocontroler and
39、DS18B20 t emperature sensor. 氯吡格雷在女性及男性应用中的相对获益及安全性 25 (J Am Coll Cardiol 2009;54:193545) 心肌梗死 ：男性 OR下降 17%，有统计学差异，女性下降 19%，都具有统计学差异，但男性与女性之间差异无统计学意义（ p=0.733） This paper mainly int roduces the design of an inteligent emperature cont rol system which realizes the function of temper at ur e measureme
40、nt and cont rol by using single bus digit al temperature sensor DS18B20 and single chip microcom puter. The core component s of the system ar e AT89C51 micr ocontroler and DS18B20 t emperature sensor. 氯吡格雷在女性及男性应用中的相对获益及安全性 26 (J Am Coll Cardiol 2009;54:193545) 大出血风险 ：男性及女性应用氯吡格雷组都有显著升高，都具有统计学差异，但男性
41、与女性之间差异无统计学意义（ p=0.243） This paper mainly int roduces the design of an inteligent emperature cont rol system which realizes the function of temper at ur e measurement and cont rol by using single bus digit al temperature sensor DS18B20 and single chip microcom puter. The core component s of the syst
42、em ar e AT89C51 micr ocontroler and DS18B20 t emperature sensor. 氯吡格雷在女性及男性应用中的相对获益及安全性 27 (J Am Coll Cardiol 2009;54:193545) 为了更好地评价获益与风险之间的平衡，每个终点都列出了需要治疗的病例数（ NNT） 净临床终点（ MI,中风，心血管死亡或大出血），尽管女性与男性之间无显著性差异，但男性似乎从氯吡格雷获益更多。随访 8.3个月， 1例获益需治疗男性 101例，女性 435例 This paper mainly int roduces the design of a
43、n inteligent emperature cont rol system which realizes the function of temper at ur e measurement and cont rol by using single bus digit al temperature sensor DS18B20 and single chip microcom puter. The core component s of the system ar e AT89C51 micr ocontroler and DS18B20 t emperature sensor. 氯吡格雷
44、在女性及男性应用中的相对获益及安全性 -结 论 28 (J Am Coll Cardiol 2009;54:193545) This paper mainly int roduces the design of an inteligent emperature cont rol system which realizes the function of temper at ur e measurement and cont rol by using single bus digit al temperature sensor DS18B20 and single chip microcom p
45、uter. The core component s of the system ar e AT89C51 micr ocontroler and DS18B20 t emperature sensor. 低分子肝素与普通肝素 29 ExTRACT-TIMI 25，国际多中心、随机双盲对照试验 入选 20479例 STEMI患者，女性 4783例（ 23%），男性 15696例（ 77%） 拟行溶栓治疗，随机 1:1分入依诺肝素组及 UFH This paper mainly int roduces the design of an inteligent emperature cont rol
46、 system which realizes the function of temper at ur e measurement and cont rol by using single bus digit al temperature sensor DS18B20 and single chip microcom puter. The core component s of the system ar e AT89C51 micr ocontroler and DS18B20 t emperature sensor. STEMI 6 小时 符合溶栓指征 由医生根据情况选择溶栓药物 (TNK
47、,TPA, rPA, SK) 普通肝素 60 U/kg 负荷剂量 ， 12 U/kg/h 维持 48 小时以上 依诺肝素 75岁 : 30 mg IV 负荷剂量 皮下 1.0 mg/kg q 12h (最多 8天或用至出院 ) 75岁 : 无负荷剂量 皮下 0.75 mg/kg q 12h (最多 8天或用至出院 ) 肌酐清除率（ CrCl ） 30: 1.0 mg/kg q 24 h 双盲双模拟期 30天随访 主要有效性终点：死亡或非致命性心梗 主要安全性终点： TIMI严重出血事件 阿司匹林 (ASA) ExTRACT-TIMI 25 研究设计 Antman EM, et al. N Engl J Med. 2006;354:1477.
