1、王春生,二尖瓣前叶成形技术 Valve Repair for Anterior Leaflet Prolapse,上海市心血管研究所 复旦大学附属中山医院心外科,二尖瓣解剖,二尖瓣解剖,Type I normal leaflet motion; Type II increased leaflet motion (leaflet prolapse); Type IIIa restricted leaflet motion during diastole and systole; Type IIIb restricted leaflet motion predominantly during sy
2、stole,Carpentier classification (revised),二尖瓣关闭不全 (N=3251),二尖瓣脱垂部位与成形概率,二尖瓣前叶脱垂病变分区 A1 、A2 、A3,二尖瓣前叶脱垂病理改变,Carpentier Type II Leaflet Motion二尖瓣前叶腱索冗长;前叶腱索断裂,治疗方法的选择 瓣膜成形 VS 二尖瓣替换,二尖瓣成形术的优点: 提高生存率; 利于左心室功能的恢复; 避免换瓣引起的:感染性心内膜炎抗凝药物相关出血性并发症栓塞,术后生存率,二尖瓣前叶成形技术,腱索转移;人工腱索(Gore-Tex);Edge-to-Edge 技术前叶部分切除;腱索缩
3、短,腱索转移 Chordal Transfer,优点: 简单; 可操作性强; 效果确切; 远期疗效佳。,适应症: 二尖瓣前叶脱垂; 腱索转移方便; 乳头肌 暴露困难;,腱索转移 Simplest Technique,腱索转移 Standard Technique,腱索转移 Standard Technique,腱索转移 Standard Technique,腱索转移 Standard Technique,腱索转移 Standard Technique,瓣环成形术 Annuloplasty,手术疗效,Reoperation: 腱索转移 VS 腱索缩短,人工腱索 Artificial Chorda
4、e,确定人工腱索的长度是关键!,人工腱索 Artificial Chordae,人工腱索 Artificial Chordae,The loop technique,The loop technique,MV repair with premeasured Gore-Tex loops results in excellent early- and mid-term outcomes for all types of leaflet prolapse. The loop technique facilitates minimal invasive MV repair without compr
5、omising surgical outcomes.,腱索转移 VS 人工腱索,Edge-to-Edge 技术 A2区,Edge-to-Edge 修复 A1、A3区,前叶部分切除 Anterior Leaflet Resection,腱索缩短 Chordal Shortening,腱索缩短 Chordal Shortening,二尖瓣前叶成形技术远期疗效评价,人工腱索(Gore-Tex) 腱索转移 Edge-to-Edge技术 前叶部分切除 腱索缩短,单纯二尖瓣脱垂 n=438,(2001.1-2007.12) 复旦大学附属中山医院心外科,二尖瓣前叶成形技术,人工腱索合并成形环修复术; 前叶三角切除/腱索转移合并成形环修复术 单纯成形环修复术; Edge-to-Edge技术,术中食道超声监测,术中TEE是判定手术效果的金标准!,结 果,围术期死亡2例(0.46),原因为术后多器官功能衰竭; 4例(0.91%)术中食道超声提示修复术后二尖瓣中重度返流,予以再次体外行二尖瓣置换术; 随访时间:6个月至6年(18.68.8月) 随访率:91.69% 5年免于再手术率97%; 术后患者心功能恢复良好。,Thanks!,