1、This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller
2、and DS18B20 temperature sensor.COPD的诊断和评估This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components o
3、f the system are AT89C51 microcontroller and DS18B20 temperature sensor.主要内容COPD的定义及发病机制新版 GOLD对 COPD的诊断及 评估This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature
4、sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.慢性阻塞性肺疾病是一种 可预防、可治疗 的常见疾病特征为 持续存在的气流受限气流受限呈进行性发展， 伴有气道和肺对有害颗粒或气体所致慢性炎症反应的增加急性加重和合并症影响患者整体疾病的严重程度COPD的定义This paper mainly introduces the design of an intelligent
5、temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.40岁以上人群患病率达 8.2% 在中国 有 4300
6、万 COPD患者是第三位死亡原因的疾病 全球范围内，与艾滋病一起名列第四大死亡原因的疾病 2002年，全球约 274万人死于 COPD 2020年， COPD将成为世界第三大死因COPD，死亡率仍在上升！COPD的流行病学 特点GOLD 2010.GOLD 2011Nanshan Zhong er al,Am J Rwspir Crit Care Med 2007,753-760This paper mainly introduces the design of an intelligent temperature control system which realizes the funct
7、ion of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.炎症机制氧化应激反应增强蛋白酶和抗蛋白酶系统失衡胆碱能神经张力增高炎症 细胞中性粒细胞巨噬细胞T淋巴细胞 B淋巴细胞 嗜酸粒细胞上皮细胞 炎症介质LTB4I
8、L-8 ,IL-6TNF-TGF-COPD的发病机制This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system ar
9、e AT89C51 microcontroller and DS18B20 temperature sensor.平滑肌功能障碍气道炎症气道重塑炎症细胞及介质 嗜酸粒细胞 肥大细胞 中性粒细胞（重度哮喘） CD4、 TH2淋巴细胞 CD4/CD8 IL-4， IL-5， IL-13COPD与哮喘炎症表达不同u哮喘的发病机制：COPD与哮喘炎症表达不同This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperat
10、ure measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.过敏哮喘吸烟 、环境污染、感染COPD大气 道小气 道小气道气道慢性炎症（气道、肺实质、肺血管）COPD与哮喘诱发炎症的危险因素、炎症的累积部位 不同This paper mainly
11、introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temper
12、ature sensor.哮喘致敏因素哮喘型气道炎症CD4+T淋巴细胞嗜酸粒细胞COPD有害物质COPD型气道炎症CD8+T淋巴细胞巨噬细胞和中性粒细胞可 逆 持续受限 COPD与哮喘诱发炎症的危险因素、炎症的累积部位 不同This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperat
13、ure sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.SystemicinflammationCOPD哮喘咳嗽、咳痰、气促 营养异常 、体重下降 骨骼肌功能障碍 心血管疾病 骨质疏松 贫血 焦虑、抑郁肺气肿和肺心病呼吸衰竭呼吸骤停气胸和纵膈脓肿过敏性肺支气管肺曲菌病综合上述：哮喘和 COPD虽然都是慢性气道炎症性疾病，但两者炎症本质不同COPD与哮喘全身炎症效应累计
14、范围不同This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontrol
15、ler and DS18B20 temperature sensor.炎症机制氧化应激反应增强蛋白酶和抗蛋白酶系统失衡胆碱能神经张力增高NF-BIL-8中性粒细募集TNF-抗氧化剂O2-, H202OH., ONOO-抗蛋白酶SLPI 1-AT蛋白酶 1-抗胰蛋白酶 分泌型白细胞蛋白酶抑制剂 弹力素 金属蛋白酶组织抑制剂中性粒细胞弹性蛋白酶组织蛋白酶基质金属蛋白酶 (MMP)1,9,12颗粒蛋白酶等COPD的 发病机制This paper mainly introduces the design of an intelligent temperature control system whic
16、h realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.气道上皮中枢神经系统迷走神经副交感神经节AChAChACh炎症细胞介质粘膜下腺毒蕈碱受体刺激物(如吸烟、细菌、病毒
17、)气道平滑肌收缩粘液分泌过多COPD胆碱能神经张力增高发病机制Peter J. Barnes， Chest， 2000This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The
18、 core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.主要内容COPD的定义及发病机制新版 GOLD对 COPD的诊断及 评估This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus di
19、gital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.Chronic Obstructive Pulmonary Disese Global Initiative for ChronicObstructiveLungDisease2013 GOLD简介 1998 COPD全球创议执行小组成立 2001 GOLD首次发布 每 5年修订一次，
20、每年更新 2011 上海发布 2013 更新发布This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are
21、AT89C51 microcontroller and DS18B20 temperature sensor.COPD的诊断 2013 GOLD 对于临床上任何有呼吸困难、慢性咳嗽或多痰，和 /或有危险因素接触史者，都应该考虑 COPD的临床诊断； 上述 患者 均 应 进行肺功能检查； 吸入支气管扩 张剂后 FEV1/FVC70%即可诊断为 COPDThis paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperat
22、ure measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.COPD的鉴别诊断This paper mainly introduces the design of an intelligent temperature control system
23、 which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.COPD的评估症状评估肺功能评估（评价气流受限的程度）急性加重风险评估合并症评估确定 疾病的严重程度，包括
24、气流受限的严重度 ，患者 健康状况，未来风险的程度，最终目的是指导 治疗目的This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of t
25、he system are AT89C51 microcontroller and DS18B20 temperature sensor.COPD的评估 症状评估p 症状评估呼吸困难评分（ mMRC评分）COPD评估测试（ CAT评分） GOLD推荐 CAT评估，没必要同时使用两种评估 CAT不是诊断 工具 ， 其 必须与其他临床评价方法联合进行 。CAT 10分 =SGRQ 25分 mMRC 1分 =CAT 3.9分This paper mainly introduces the design of an intelligent temperature control system whic
26、h realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.COPD的评估 -气流受限程度 症状 评估 肺功能评价气流受限的程度Grades 废除This paper main
27、ly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 tem
28、perature sensor.COPD的评估 急性加重风险 症状 肺功能评价气流受限的程度 急性加重风险的评估在 过去一年内急性 加重发作 2次及以上，或因病情加重 1次住院考虑为高风险FEV1 50 %预计值的 COPD患者，提示急性加重的风险大。This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus di
29、gital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.COPD的评估 合并症评估 症状 肺功能评价气流受限的程度 急性加重风险的评估 合并症的评估评估合并症并相应治疗。最常见的合并症是 CVD、抑郁和骨质疏松。可发生于轻度、中度、重度和极重度患者。This paper mainly introduces the design of an
30、intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.（ C）高危较少症状（ D）高
31、危较多症状（ A）低危较少症状（ B）低危较多症状风险(急性加重病史)风险(气流受限的GOLD分类)4321210mMRC 2CAT 10mMRC 2CAT 10 症状(mMRC或 CAT评分 )患者 特征 肺功能分级 急性加重次数 /年 mMRC CATA 低风险、症状较少 GOLD1-2 1 0-1 10B 低风险、症状较多 GOLD1-2 1 2 10C 高风险、症状较少 GOLD3-4 2 0-1 10D 高风险、症状更多 GOLD3-4 2 2 102013 GOLD评估风险时，选择 GOLD 分级或急性加重病史最高风险 （因病情加重住院 1次考虑为高风险）COPD的综合 评估Thi
32、s paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and
33、 DS18B20 temperature sensor.COPD的综合评估- 反映 了 COPD的复杂性，明显 优于既往应用 单一的气流受 限对 COPD进行 分期，其最终 目的是更加合理的指导患者的治疗。COPD的综合 评估This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital tempera
34、ture sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.总 结 COPD和哮喘虽然都是慢性气道炎症性疾病，但两者炎症本质不同 胆碱能神经张力增高是重要发病机制之一 吸入 支气管扩张 剂后 FEV1/FVC70%即可诊断为 COPD 2013 GOLD对 COPD采用综合评估，如因病情加重导致住院 1次考虑为高风险This paper mainly introduce
35、s the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.谢谢 谢！谢！
