1、* “:SE1 S( 50363001) ,SE/ 86309( 2003AA33X080) ,L 81 S( 20033082) ,L 8 ,L 8O.季铵盐类抗菌剂及其应用研究进展*佟 会1, 2 邱树毅1, 2, 3( 1.L 8? 30 L i,LL, 550003; 2.Lv,LL, 550003; 3.L 8 7,LL, 550000)K 1 8 S =11 F )4!a F ) ?# F ) Z,i ?ZT Zb1oM 1 F )4 F ) ms | TQ113. 79 DS M A cI| 1008- 9411( 2006) 05- 0001- 07前 言“ 3 4, 31 p
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4、C T,74V 18 )8? 3v s ,V7% ) b 10YV% ) = T1 F ) , L ,F T 1 )A F F )4 )A,A % = , %C % =? 3 ? A/bYV 4?C F)4T% )% “ A,%C ,s b F ) VByT%C73 )Tb2 高分子季铵盐抗菌剂的应用研究“ - F ) $ ,.Z1h4s ? k4 J .Sh, 2005, 22( 2) : 187 189. 13 ,.1h4 )rT k4 J .Sh, 2000, 17( 1) : 31 33. 14 NudeI R. Janauer G E, Schrier E E, et al. US
5、4 349 646 P . 1980.#6# 贵 州 化 工Guizhou Chemical Industry2006 年10 月第31 卷第5 期 15 , S,.V 1s0 F)V+ J .n, 2003, 24( 6) : 1131 1135. 16 Joerg C, Alexander M . Polymer surface derivatized withpoly( vinyl- N- hexylpyridinium) kill airborne and w a-terborne bacteria J . Biotechnol Bioeng, 2002, 79 ( 4) :465.
6、17 Lin Jian, Qiu Shuyi, Klibanov AM . Bactercidal propertiesof flat surfaces and nanoparticles derivatized with alky-lated polyethylenimines J . Biotechnol Prog, 2002, 18:1082. 18 Lin Jian, Qiu Shuyi, Klibanov AM . M echeanism of bacte-ricidal and fungicidal activities of textiles covalently mod-ifi
7、ed w et h alkylated polyethylenimine M . Wiley Period-icals, Inc, 2003. 19 k,k.,;1 F ) Y !V J .s0, 2005( 1) : 157 160. 20 Kim Lew is, Alexander M . Klibanov. Surpassing nature :rational design of sterile- surface materials. Trends inBiotechnology, 2005, 23( 7) : 343- 348. 21 ,f .1 F )4!# ? J . ? , 2
8、005, 36( 12) : 1872 1878. 22 f ,*, .1 r F )# F ) J .A , 2006, 34( 1) : 87 92. 23 S,.V 1 88- ) J .s0, 2004( 1) :107 113. 24 Kaw abata N, Nishiguchi M . Antibacterial activity of so-luble pyridinium - type polymers J . Appl Environ M -icrobiol, 1998, 54( 10) : 2532 2535. 25 T. E. Cloete. Resistance me
9、chanisms of bacteria to an-t imicrobial compounds. International Biodeteriorat ionBiodegradation , 2003, 51: 277 282. 26 ,E . Jb:1 K ) J .q F, 2004, 26( 4) : 158160. 27 Viktor M ajtan, Lubica M ajtanova. The effect of new dis-infectant substances on the metabolism of Enterobactercloacae J . Internat
10、ional Journal of Antimicrobial A-gents, 1999, 11: 59 64. 28 gZ a. T # 1a F )Z J . / , 2005, 27( 9) : 5 7. 29 g , “ 3, l. F ) 4A1ASQA# J . 4, 2005, 22( 1) :20 23. 30 S i, ,f . F ) )rT_ J .Chinese Journal of Disinfection, 1996, 13( 2) : 98. 31 fk,l +, 7.A1 F ) 3 4HK - 2002 J . 4,2003, 20( 5) : 29 30.
11、32 CHANG- WOO NAM , Young- Ho Kim, Sohk - Wonko. M odification of polyacrylonitrile fiberby blendingweth N- ( 2- hydroxy) propyl- 3- trimethyl- ammo-nium chitosan chloride J . Journal of Applied PolymerScience, 1999. 33 HA - SOO SEONG, Hyun Suk Whang, Sohk - WonKo. Synthesis of a quanternary ammoniu
12、m derivative ofchitooligosaccharide as ant imicrobial agent for cellulosic J . Journal of Applied Polymer Science, 2000. 34 0 3, ;. TS- 838 )4 ? J . ) , 2003, 23( 9) : 61 62. 35 U,o .? s0 ? ) 4FIO- C!# J . ) , 2001, 21( 1) :13 16. 36 =.1 0V 4?Z# J .D ! v(1 S) , 2003, 21( 4) : 503 506. 37 Akihiko Kan
13、azawa, Tomiki Ikeda, Takeshi Endo. Poly-meric phosphonium salts as a novel class of cationic bio-cides : Synergistic effect on antibacterial activity ofpolymeric phosphonium and ammonium salts J . J ApplPolym Sci, 1994, 53: 1245 1249.( l 2006- 07- 28)Te , o, V 3,Z_: F ) ? ; nj, q,p VbProgress of Qua
14、ternary Ammonium Salt and Application ResearchT ong H ui1, 2 Qiu Shuyi1, 2, 3*( 1. Guizhou Province Key Laboratory of Fermentation Engineering and Biopharmacy, Guiyang, 550003; 2. Co-llege of Chemical Engineering, Guizhou U niversity, Guiyang, 550003; 3. Guizhou Province Base of New M aterialT echni
15、que Innovation, Guiyang, 550000)Abstract:In this article author review ed the processing, antibacterial properties and mechanism of quaternaryammonium salt. Their application and developm ent trend of quaternary ammonium salt in different fields as ger-m icidal w as described and discussed.Key words:Quaternary ammonium salt; antibacterial material; antibacterial mechanism; application#7# 2006年 10 月第31卷第 5期 佟 会等:季铵盐类抗菌剂及其应用研究进展
