1、 ,ZHEJIANG XINAN CHEMICAL INDUSTRIAL GROUP CO.,LTD.,Development of non-selective herbicide in China, glyphosate,ZHEJIANG XINAN CHEMICAL INDUSTRIAL GROUP CO.,LTD. Zhou shu-guang,Development of glyphosate industry; Production of global and Chinas glyphosate; Technology improvement of Chinas glyphosate
2、; Development of glyphosate formulation; Competitiveness of Chinas glyphosate in the global market; Challenges facing Chinas glyphosate industry and the future of Chinas glyphosate industry.,Content:,Part 1- Development of glyphosate industry,Glyphosate (N-(phosphonomethyl)-glycine), is non-selectiv
3、e and broad-spectrum herbicide for the annual and perennial deep-rooted weeds in many crops. It was commercialized by Monsanto Corporation in 1974,and often used in forestry, orchards, non-farmland and No-Till because of its non-selectivity.,H,N,P,O,COOH,OH,OH,Molecular formula:,PMG:,Glyphosate intr
4、oduction,CH2,Production process,DEA,IDAN,IDA,PMIDA,PMG,IDA,GLY,synthesize,PMG,hydrolyze,Gly,DMP,etc.,Addition reaction:,Condensation reaction:,Hydrolyzation reaction:,Glyphosate industry development,In 1970s, IDAN route to produce PMG was first developed by Monsanto Corporation. process flow is foll
5、owing:,In 1990s, Monsanto Corporation replaced IDAN route by DEA route. process flow is following:,HCN,IDAN,PMIDA,PMG,Producing acrylonitrile process,C2H4,DEA,PMIDA,PMG, Monsanto, China,In 1986, GLY route to produce PMG which was developed by Shenyang Institute of Chemical Industry successfully tria
6、l produced in Zhejiang Jiande and Jiangsu Jiangnan chemical factory. Meanwhile, production technique of 10% PMG aqua was developed.,chloroactic acid,In 1996, DEA route to produce PMG bring about industrialization and batch dehydrogenation process was mature.process conditions and results:reaction ye
7、ild of IDA is 92%;reaction pressure is from 16 to 19 kgf/cm2;reaction temperature is from 160 to 190 .,PMIDACa,10% PMG aqua,In 2003 to 2004, IDAN production process from natural gas and PMIDA production process were well developed.,In 2000, IDAN production process was developed by Sichuan Chemical A
8、cademy of Natural Gas.,Glyphosate development state from 1982 to 2008 in China,1: production capacity (kt/a) 2: production (kt/a),Change of Production capacity and production from 1985 to 2008 in China,Grow trend of global glyphosate demand,kt/a,Consumption of global glyphosate,The rate of annual gr
9、owth for glyphosate is 28% between 19962007. Growth of PMG is rapidly in 2008.,PMG,Consumption (kt/a),year,With the expanding cultivation of global genetic modified crops, and the recovery and modernization development of global agriculture, particularly in developing countries, the demand for glyph
10、osate grows rapidly and it has become a kind of agrochemical with the worlds largest sales and the fastest growth rate. At present global glyphosate production accounted for 30% of the total herbicide market. China is the largest producer nation of glyphosate in 2008, Chinas production of glyphosate
11、 is almost 390,000 tonnes, of which nearly 80% for export.,Part 2- Production of global and Chinas glyphosate,Production state of Monsantos glyphosate,Monsanto is still the largest global producer of glyphosate, accounting for 40% of global production.In 2006, Monsanto stops a set of production equi
12、pments of glyphosate and starts to purchase technical glyphosate from China to make up for its shortage in 2007.In 2008, Monsanto announces that a set of new production equipments of glyphosate will be built, which would start to produce at least in 2010. That is to say, its production of glyphosate
13、 will be 240,000 tonnes per year.,Production state of Chinas glyphosate,After 2005, Chinas glyphosate industry grows rapidly.,New and expanding production projects of glyphosate reach a fastigium from 2005 to 2008, for example, Zhejiang Xinan Chemical Industrial Group Co.,Ltd., Nantong Jiangshan Agr
14、ochemical, Sichuan Leshan Fuhua Chemical. China become the largest producer and provider nation of glyphosate now.,Forecast that Chinas glyphosate production would reach 500,000 tonnes in 2010. Zhejiang Xinan Chemical Industrial Group Co.,Ltd. is the largest producer of glyphosat in China, its produ
15、ction capacity is 80,000 tonnes per year in 2009.Production capacity of glyphosate of Nantong Jiangshan Agrochemical Group Co.,Ltd. is 70,000 tonnes per year in 2009.(Production capacity of IDA and GLY process is 40,000 and 30,000 tonnes per year.),Table: Increase of production capacity of Chinas gl
16、yphosate,Conclusion: It is a fastigium of new and expanding projects in 2008. New increase in production capacity of PMG is 368,000 tonnes in the end of 2008, of which IDA process of 57 percent and GLY process of 43 percent.,Glyphosate manufacturers in China Glycine process- production capacity in 2
17、008,1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14.,Zhejiang Xinan Chemical Sichuan Leshan Fuhua Chemical Nantong Jiangshan Agrochemical Hangzhou Agrocn Industry Sichuan Berer Shandong Rainbow Chemical Jiangsu Tenglong Chemical Ningxia Sanxi Chemical Jiangsu Fengshan Zhejiang Linghua Industry Yongzho
18、u Guangfeng Agriculture Chemical Fujian Sannong Anhui Guangxin Agrochemical Shandong Binnong,80000t 45000t 27000t 24000t 20500t 20000t 20000t 20000t 15000t 12000t 12000t 10000t 10000t 10000t,Glyphosate manufacturers in China IDA process-production capacity in 2008,1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11.
19、12. 13. 14.,Jiangsu Youth Chemical Anhui Huaxing Chemical Industry Jiangsu Anpon Electrochemical Shandong Qiaochang Chemical Zhejiang Biok K. P. Chemical zhenjiang Jiangnan Chemical (Xinan ) Zhejiang Longyou Greenland Pesticides Yichang Xingfa Chemicals Jiangsu Kuaida Agrochemical Shandong Vicome Gr
20、eenland Chemical Hubei Sanonda Suzhou Jiahui Chemical Jiangsu Good Harvest-Weien Agrochemical Anhui Chloro-Alkali Chemical,40000t 35800t 33000t 30000t 27170t 25000t 20000t 20000t 15000t 15000t 15000t 15000t 12000t 10000t,PMG price / RMB,Month from 2007 to 2008,Production of global Glyphosate (440,00
21、0 tonnes) in 2007,China 52%,Monsanto 40%,others 8%,Production of global Glyphosate (606,000 tonnes) in 2008,China 64%,others 6%,Monsanto 30%,The expanding cultivation of global genetic modified crops and the rapid development of bio-fuels promote the strong demand for herbicides market. Glyphosate i
22、ndustry will become into the biggest beneficiaries, because of genetic modified crops flourish. At present there is no new herbicide varieties which could replace glyphosate in the world, considering technical and commercial value. The demand for glyphosate grows rapidly, the market boom can be main
23、tained at least over 10 years.,Part 3-Technology improvement of Chinas glyphosate,Petroleum,DEA,IDA,Glycine,IDA process,Glycine process,Natural gas,IDAN,IDA,IDA process,Epoxyethane,HCN,Process introduction,chloroactic acid,PMG,Discover chloromethaneown invention patent;application of organosilicon p
24、roduction. Complete large scale and autocontrol of PMG production plant. Develop continuous production technology. After using new process, energy consumption and PMG ML will decrease and yield of PMG will increase.,Technical progress of glycine process,Technical progress of IDA process,Mature produ
25、ction IDAN process.,Chongqing Unisplendour Chemical Co.,Ltd. build up 100,000 t/a IDAN production plant and another 100,000 t/a is its new projects.Waste treatment for production IDAN process developed by Shenyang Institute of Chemical Industry bring about industrialization. Production capacity of I
26、DAN which will be building by Shanghai Chemical, Sichuan Chemical Academy of Natural Gas etc. will exceed 100,000 t/a.,Large scale PMIDA production plant from IDAN in China. DEA continuous dehydrogenation process.,PMIDA oxidation process has more progress.,High concentration PMIDA batch oxidation pr
27、ocess.,Special oxidation reaction pot and oxygen distributing.conversion of PMIDA 98%, selectivity of PMG 96%. Special controller of oxidation end point.avoid side reaction of PMG conversion to AMPA,PMIDA to PMG:,PMG to AMPA:,Comparability of different oxidation process,Special solvent filtration,us
28、e mix-solventbase on difference of PMG solubilityreplace existing salt filtration process,Membrane filtration equipment applied in PMG mother liquor.,resoure reuseinglow energy consumptionfriendly environment,advantage,PMGmother liquor,pretreatment,multilevel Membrane system,Crystalization filtratio
29、n,PMG,Biochemical sewage treatment,10 PMG aqua,Part 4- Development of glyphosate formulation,Development of PMG formulation,Formulation,Aqueous Solution (AS),Soluble powder (SP),Soluble granule (SG),time,10% glyphosate sodium salt AS：200 thousands ton per year.41% glyphosate isopropylamine salt AS：p
30、opular in the world.62% glyphosate isopropylamine salt AS ：used to mix 41% AS.The others： PMG ammonium salt AS、PMG potassium salt AS、 PMG dimethylamine salt AS .,PMG AS,Global distribution of PMG AS,PMG SP and SG,PMG SP:30% PMG ammonium salt SPPMG SG：74.7% PMG ammonium salt SG (Monsanto)75.7% PMG am
31、monium salt SG (Wynca),Series Products of PMG formulation,PMG water-based-formulation,PMG sodium salt AS,PMG dimethylamine salt AS,PMG isopropylamine salt AS,PMG potassium salt AS,Mixed formulation,2，4-D + PMG,The others,SG,PMG ammonium salt SG,PMG potassium salt SG,PMG isopropylaminesalt SG,Acetoch
32、lor + PMG,Development of adjuvant used in PMG formulation,Tallow Amine,APG,Organosilicon Adjuvant,New PMG SG of Wynca,75.7 PMG ammonium salt SG,Sale of PMG ammonium salt SG of Wynca,PMG potassium salt SG,PMG isopropylamine salt SG,Character of new PMG SG are:high ingredient more effectiveness better
33、 activity convenience environmental friendly formulation,Part 5- Competitiveness of Chinas glyphosate in the global market,Competitiveness of glyphosate for glycine route,High atom economy, such as chlorine atom cycle between PMG and organosilicon production used by Zhejiang Xinan Chemical Industria
34、l Group Co.,Ltd. All of problems of Engineering technique be resolved.,continuous recovery of solvent, catalystDCS control system application,Complete, enough supply of raw material of production PMG. Technique of waste treatment is mature.,Chlorine Cycle of Wynca,Wyncas factory picture,Competitiven
35、ess of glyphosate for IDA route,Engineering technique is no problem now,large scale PMG production plant for DEA and IDAN processcontinuous dehydrogenation technique developed have technique of PMIDA mother liquor disposal in China and Monsanto use landfill method.high concentration PMIDA batch oxid
36、ation procees in China, which filtration technique is perfect. membrane filtration technique applied in PMG ML only in China.,Obvious advantage of cost than the others,Part 6- Challenges facing Chinas glyphosate industry and the future of Chinas glyphosate industry,Make PMG production plant Large scale and continuous to reach international level. Development of formulation product, especially in mixed formulation. Develop waste disposal technique.,Challenges：,A combination of large PMG manufacturer.Do PMG overseas registration.GLP laboratory is being set up.,Future：,thank you！,
