1、Limitations,lack of knowledge,The minimization of radiation dose辐射剂量 to the subject is an attractive feature of the use of short-lived radionuclides短寿期放射性核素 . Besides its established role as a diagnostic technique诊断技术, PET has an expanding role as a method to assess the response to therapy, in parti
2、cular, cancer therapy肿瘤治疗,where the risk to the patient from lack of knowledge about disease progress is much greater than the risk from the test radiation.,high costs,cyclotrons 回旋加速器 to produce the short-lived radionuclides for PET scanningchemical synthesis apparatus 化学合成装置 to produce the radioph
3、armaceuticals after radioisotope preparation most clinical PET is supported by third-party suppliers of radiotracers 放射性示踪剂 that can supply many sites simultaneously.,Limited time,Because the half-life of fluorine-18 is about two hours, the prepared dose of a radiopharmaceutical bearing this radionuclide will undergo multiple half-lives 半衰期of decay during the working day,