1、骨关节炎、运动损伤与胶原蛋白Osteoarthritis osteoarthritis, athletic injury and collogen骨关节炎Osteoarthritis 骨关节炎(osteoarthritis)又名退行性骨关节炎，为关节软骨发生退行性变，并在关节边缘有骨刺形成。骨关节炎多见于老年人，随着人类平均寿命的延长，骨关节炎的发病率愈来越高，它严重妨碍工作，成为 50 岁以后丧失劳动力的第二个常见原因。The osteoarthritis other name recession osteoarthritis, has the degeneration for the ar
2、ticular cartilage, and has the spur formation in the joint edge. The osteoarthritis sees in the senior citizen, along with the human mean lifetimes extension, osteoarthritiss disease incidence rate comes to be higher, it hinders the work seriously, will become 50 year old of later disabled the secon
3、d common reason. 骨关节炎可分为原发性和继发性骨关节炎两大类，原发性主要为关节软骨的退行性老化病变，随着年龄的增长而日渐加重，软骨是所有结缔组织中老化现象较显著的组织，软骨老化是正常的生理演变，但可以在遗传的基础上因人而异，有的发生较早，比较快速，也有的发生较晚，较缓慢，一般病情进展与疲劳过度及关节负担过重有关。继发性骨关节炎即先有其它疾病如先天性发育异常、外伤、骨骼的缺血坏死、下肢不等长及畸形等，而逐渐导致关节软骨的病变。此外，骨关节炎还可能因不适当地长期大量激素及局部的放射线治疗所引起。The osteoarthritis may divide into primary a
4、nd the sequential osteoarthritis two broad headings, the primary stage mainly for articular cartilages recession aging pathological change, along with age growth, but aggravates day after day, the cartilage is all knots contracts in the organization the ageing phenomenon remarkable organization, the
5、 cartilage aging is the normal physiological evolution, but may be different from person to person in the heredity foundation, some occurrences, are quite early fast, some occurrences are also late, is slow, generally the condition progress and weary excessively and the joint burden concerns overwei
6、ght. The sequential osteoarthritis namely has other disease like congenitalness growth exceptionally, the flesh wound, skeletons ischemia necrosis, the lower limb not to wait for long and abnormal and so on first, but causes articular cartilages pathological change gradually. In addition, because th
7、e osteoarthritis also possible not suitably the long-term massive hormones and the partial radioactive rays treatment cause. 肥胖患者关节负重增加，人体为维持重心会发生膝部的内翻畸形，使膝关节两侧间隙负重不平衡，导致退行性变，积累性的微小损伤可造成软骨下骨的硬化改变，影响关节软骨对关节负重的抵抗力，导致软骨的退变，上下楼梯滑一下看起来不重的损伤，能在很短的时间内传递给关节软骨过重的负荷。The obese patient joint carries a heavy loa
8、d increases, the human body will have knees in for the maintenance center of gravity to turn abnormally, will cause the knee joint both sides gap to carry a heavy load not balanced, will cause the degeneration, the accumulation small damage to be possible to create under the cartilage bones hardened
9、 change, will affect the articular cartilage the resistivity which will carry a heavy load to the joint, will cause the cartilage to draw back changes, the high and low staircase will slide looks like not the heavy damage, can give the articular cartilage overweight load in the very short time biogr
10、aphy.性别与骨关节炎的发生也密切相关，女性在绝经前其骨关节炎的发生与男性相似，但到绝经期以后，女性骨关节炎的发生率明显高于男性。特殊职业的人群中，其骨关节炎的发生率也较高，如矿工由于长期处于半蹲或蹲位，且需用肘关节，而引起膝、肘关节骨关节炎发生增加；我国广大农村地区，有些地区的农民需采摘棉花或工厂的纺织女工，其手关节骨关节炎也较常见。The sex and osteoarthritiss occurrence closely is also related, the female its osteoarthritiss occurrence is similar before the me
11、nopause with the male, but after the menopause, the feminine osteoarthritiss formation rate is higher than the male obviously. In the special occupations crowd, its osteoarthritiss formation rate is also high, like miner, because is in for a long time partly squats or squats the position, and needs
12、the elbow joint, but causes the knee, the elbow joint osteoarthritis to occur increases; Our country general countryside area, some areas farmer must pick the cotton or the factory textile female worker, its articular arthritis is also common. 当人体渐趋老化，或因创伤或疾病，关节软骨出现退化，逐渐出现断裂、失去弹性，随之发生裂缝、糜烂与溃疡，使软骨表面呈
13、毛刷状，粗糙不堪。不光滑的软骨面相互摩擦，使软骨损毁更进一步加重。这时关节软骨的完整性就遭到破坏。关节软骨基质分解和合成失调造成软骨的进一步破坏，软骨下骨板由于缺乏软骨的保护，局部受到异常的压力而发生代偿性增生(骨刺形成)，严重影响人们的生活。When the human body tends to be the aging, either because of the wound or disease, the articular cartilage presents the degeneration, presents the break, to lose the elasticity g
14、radually, has the crack, the erosion and ulcer along with it, causes the cartilage table delivering in person hair brush shape, is unable to withstand roughly. Not the smooth cartilage surface rubs mutually, causes the cartilage damage further aggravation. By now articular cartilages integrity was d
15、estructed. The articular cartilage matrix decomposition and synthesis being out of balance create cartilages further destruction, under the cartilage the bone board, because lacks cartilages protection, receives the unusual pressure to have the redemptive proliferation partially (spur to form), seri
16、ous influence peoples life.运动损伤Athletic injury 现在，越来越多的人在运动和工作时出现关节强直和疼痛症状，尤其是运动员和老年人，即使有充分的营养和锻炼，仍然会发生一些软骨磨损和撕裂的情况。运动员和健身者经常处于大量韧带和关节拉紧的状态，并导致损伤。随着年龄的增长，相连组织间的磨损也有导致病变的倾向。而且随着年龄的增长，维护关节的健康也更加困难，而体重超标或者剧烈运动会使情况进一步恶化。Now, more and more people when movement and work presents the joint strong straight
17、and the ache symptom, particularly athlete and senior citizen, even if has the full nutrition and the exercise, still will have some cartilage attrition and the tearing situation. The athlete and the fitness are at the condition which frequently the massive ligaments and the joint tighten, and cause
18、s the damage. Along with the age growth, during the connected organizations attrition also has causes pathological changes tendency. Moreover along with the age growth, maintains joints health to be also more difficult, but body weight exceeding the allowed figure or the fierce games cause the situa
19、tion to further worsen. 颈椎病是一种高发病，由于颈椎间盘退行性变、颈椎骨质增生所引起的一系列临床症状的综合征。颈椎病可分为颈型、神经根型、脊髓型、椎动脉型、交感神经型和其他型，临床常表现为颈、肩臂、肩胛上背及胸前区疼痛，臂手麻木，肌肉萎缩，甚至四肢瘫痪。Cervical vertebra sickness is one kind of high morbidity, because the neck intervertebral disc degeneration, the cervical vertebra ossein proliferation causes a
20、series of clinical symptoms syndrome. Cervical vertebra sickness may divide into the neck, the nerve root, the spinal cord, the arteria vertebralis, the nerve and other, clinical often displays for the neck, the shoulder arm, the scapula upper back and the front area ache, the arm is numb, ischemic
21、muscular atrophy, even four limbs paralysis. 该病可发生于任何年龄，以 40 岁以上的中老年人为多。该病具有发病率高，治疗时间长，治疗后极易复发等特点。颈椎病是多种疾病的根源，其退行性病变是一个长期、缓慢的过程，并非一日之寒。因此，我们提醒您要重视早期锻炼和颈椎病的预防保健，只有早发现、正确治疗，才能拥有健康的生活。Should sickness be possible to occur in any age, by 40 year-old above middle and old age artificial many. This sickness
22、 has the disease incidence rate to be high, the treatment time is long, after the treatment, is extremely easy to recur and so on characteristics. Cervical vertebra sickness is many kinds of diseases roots, its recession venereal diseases change are long-term, the slow process, and Rome was not buil
23、ts in a day. Therefore, we remind you to take the prevention health care which the early exercise and the cervical vertebra get sick, only then discovered early, the correct treatment, can have the health life. 造成颈椎病的原因，医学界认为主要有以下两个方面：一是退变，随着人体的衰老，椎间盘周围纤维环老化，体积缩水，使椎关节失稳。二是急性损伤和慢性劳累。大部分中青年患者的致病原因主要是后
24、者。具体分析有以下 4 方面的原因：长时间一种姿势低头作业、不良坐姿和卧姿、高枕及颈椎损伤。Creates the reason which the cervical vertebra gets sick, the medical arena thought that mainly has the following two aspects: First, draws back changes, along with human bodys senility, around the intervertebral disc the textile fiber link gets older, t
25、he volume shrinkage, causes zhui the joint jitter. Second, acute damage and chronic tired. The majority of middle-aged patients pathogenicity is mainly the latter. The concrete study has the following 4 aspect reason: The long time one kind of posture lowers the head the work, the bad sitting postur
26、e and the prone position, Gao Zhen and the cervical vertebra damage.胶原蛋白维持关节健康Collogen maintenance joint health 生活中，这些关节疾病给我们带来很多麻烦，关节红、肿、涨、痛，上楼上不去，下楼下不来，走路走不动，动不动就腿痛、腰痛、胳臂痛。这些都与体内的胶原蛋白的缺乏有直接关系。In the life, these joint illness gets sick to us brings troublesome, the joint red, swells, rises, the pai
27、n, goes upstairs cannot come up, goes downstairs cannot get down, walks cannot take a walk, often on leg pain, lumbago, arm brachialgia. These deficient have the direct relation with in vivo collogen.胶原蛋白(collagen) 是人体内一种与组织和器官功能有关的功能性蛋白，富有多样性及组织分布的特异性。胶原蛋白主要分布在哺乳动物的结缔组织中，对动物和人体皮肤、血管、骨骼、筋腱和软骨等的形成都十分
28、重要，是这些结缔组织的主要基质。胶原蛋白在高等动物机体中的含量丰富，约占蛋白质总量的1/3。其中，皮肤总重的 70%为胶原蛋白，而软骨中几乎都是胶原蛋白，肌腱、筋中胶原蛋白纤维占80%。Collogen is in the human body one kind with the organization and the organ function related functionality protein, rich multiple and organization distributed specificity. The collogen mainly distributes, in
29、mammals knot contracts in the organization, to the animal and the human body skin, the blood vessel, the skeleton, the tendon and the cartilage and so on formation is very important, is these knots contracts organizations main matrix. Collogens is rich in higher animal organism content, approximatel
30、y composes the protein total quantity 1/3. And, the skin gross weight 70% are the collogen, but in the cartilage nearly is the collogen, in the tendon, the muscle the collogen textile fiber accounts for 80%.由于胶原蛋白是关节中软骨组织的主要成分，负责构造软骨组织的框架并将其定型。因此，补充适量的胶原蛋白，可以维持人体自身软骨组织的自动生成机制，保护关节免于磨损和毁坏，也可预防由各种原因引发
31、的骨关节炎。Because the collogen is the joint medium-soft bone tissue principal constituent, is responsible to construct Cartilage tissues frame and its stereotypia. Therefore, supplemented that the right amount collogen, may maintain the human body own Cartilage tissues automatic production mechanism, pr
32、otects the joint avoid the attrition and the destruction, may also prevent the osteoarthritis which initiates by each kind of reason.胶原蛋白用于药物及食品已有较长的历史。临床研究表明，每日摄入一定的胶原蛋白可减轻膝或髋部骨关节病患者的疼痛，血中羟脯氨酸浓度升高。一家德国研究中心的数据表明，胶原蛋白组与安慰剂组相比有显著治疗效果。对于在研究之初即有重度临床症状的病人，胶原蛋白比安慰剂有更加显著的治疗效果。有报导称 14C 标记的胶原蛋白将比 14C 标记的脯氨酸优
33、先聚集在软骨中，这种优先摄取显示胶原蛋白在软骨代谢中有增效作用。The collogen using in the medicine and food had the long history. The clinical research indicated that takes in certain collogen to be possible every day to reduce the knee or the hip department osteoarthropathy patients ache, in the blood the hydroxyproline density e
34、levates. A Germany Research centers data indicated that the collogen group and the placebo group compare have the remarkable treatment result. Regarding namely has the specific weight clinical symptoms patient at the beginning of the research, the collogen has the more remarkable treatment result compared to the placebo. Some reports said that the 14C mark the collogen first will gather compared to the 14C marks proline in the cartilage, this kind first absorbs the demonstration collogen to have the synergized action in the cartilage metabolism.
