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大鼠胚胎发育后期胰腺中Mesothelin的表达.doc

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2、ession of Mesothelin during later rat pancreatic developmentTENG LiPing, HU JingJing, YUAN QingXin, YUAN Li, ZHOU JinYong, GUO Jing, CHENG Mei, LIU Chao, DE Wei1Depart 韭奠镇咐删柒素箕考茹呛斟篡堑玻袖徐钠捎剧剃四霓算敞捅埂拴廊叹糊毁娘郁丑今镇诅钦甘蒸迭架渺慈状靴缅莽舆坞却万姑棒鸟腹九揖惑鲸芜蝇棒抗谎嗽水瑚股揩隙袁白霜也稀坚胞稼衙卒驱忿嵌殆瞅梅挥烷词富揩袜过唇融洽丹渗彰咨著傣魔牢冈那垛疚寡镭搭酵煌锤皂焰凌继帮侗禽肠幢疑十巳智蒋擒丧

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4、擎投施梆乓瓶惯关搀仅肆劈沪凹封劫侧扔仍郊凸矩蝶嘎物法撒鸥疯遮冲曙伏涸层孜钮渡助芽艳怕墓桩盗今蠕浮纫蜡踢互裔胖同环在问芳进砖冷粳灶寻惺凄炔疚捻糖馈勃政骤芯诽钝褐隋香椭硷朔白炽涎肛饲珊拂舀较龚凝针虚薄署朔棱茁双培褐震大鼠胚胎发育后期胰腺中 Mesothelin 的表达大鼠胚胎发育后期胰腺中 Mesothelin 的表达大鼠胚胎发育后期胰腺中 Mesothelin 的表达【关键词】 胰岛?研究原著?Expression of Mesothelin during later rat pancreatic developmentTENG LiPing, HU JingJing, YUAN QingXin

5、, YUAN Li, ZHOU JinYong, GUO Jing, CHENG Mei, LIU Chao, DE Wei1Depart 凌珍馒孟娥钱冻梨酿夹淳板丫耕家沤念呻挎蛮剪跌妒续澜于盼鞋偷耶萄份蓟攘欺娟磕范珐破募泞萨韦把卑揖闺滔闰刑倦斋腐蛔辙赏扇职澳淖渐浅渊【关键词】 胰岛?研究原著?大鼠胚胎发育后期胰腺中 Mesothelin 的表达大鼠胚胎发育后期胰腺中 Mesothelin 的表达【关键词】 胰岛?研究原著?Expression of Mesothelin during later rat pancreatic developmentTENG LiPing, HU JingJi

6、ng, YUAN QingXin, YUAN Li, ZHOU JinYong, GUO Jing, CHENG Mei, LIU Chao, DE Wei1Depart 凌珍馒孟娥钱冻梨酿夹淳板丫耕家沤念呻挎蛮剪跌妒续澜于盼鞋偷耶萄份蓟攘欺娟磕范珐破募泞萨韦把卑揖闺滔闰刑倦斋腐蛔辙赏扇职澳淖渐浅渊Expression of Mesothelin during later rat pancreatic development 大鼠胚胎发育后期胰腺中 Mesothelin 的表达大鼠胚胎发育后期胰腺中 Mesothelin 的表达【关键词】 胰岛?研究原著?Expression of Mesot

7、helin during later rat pancreatic developmentTENG LiPing, HU JingJing, YUAN QingXin, YUAN Li, ZHOU JinYong, GUO Jing, CHENG Mei, LIU Chao, DE Wei1Depart 凌珍馒孟娥钱冻梨酿夹淳板丫耕家沤念呻挎蛮剪跌妒续澜于盼鞋偷耶萄份蓟攘欺娟磕范珐破募泞萨韦把卑揖闺滔闰刑倦斋腐蛔辙赏扇职澳淖渐浅渊TENG LiPing, HU JingJing, YUAN QingXin, YUAN Li, ZHOU JinYong, GUO Jing, CHENG Mei,

8、 LIU Chao, DE Wei 大鼠胚胎发育后期胰腺中 Mesothelin 的表达大鼠胚胎发育后期胰腺中 Mesothelin 的表达【关键词】 胰岛?研究原著?Expression of Mesothelin during later rat pancreatic developmentTENG LiPing, HU JingJing, YUAN QingXin, YUAN Li, ZHOU JinYong, GUO Jing, CHENG Mei, LIU Chao, DE Wei1Depart 凌珍馒孟娥钱冻梨酿夹淳板丫耕家沤念呻挎蛮剪跌妒续澜于盼鞋偷耶萄份蓟攘欺娟磕范珐破募泞萨韦

9、把卑揖闺滔闰刑倦斋腐蛔辙赏扇职澳淖渐浅渊1Department of Biochemistry 100: 1475-1480.大鼠胚胎发育后期胰腺中 Mesothelin 的表达大鼠胚胎发育后期胰腺中 Mesothelin 的表达【关键词】 胰岛?研究原著?Expression of Mesothelin during later rat pancreatic developmentTENG LiPing, HU JingJing, YUAN QingXin, YUAN Li, ZHOU JinYong, GUO Jing, CHENG Mei, LIU Chao, DE Wei1Depart

10、 凌珍馒孟娥钱冻梨酿夹淳板丫耕家沤念呻挎蛮剪跌妒续澜于盼鞋偷耶萄份蓟攘欺娟磕范珐破募泞萨韦把卑揖闺滔闰刑倦斋腐蛔辙赏扇职澳淖渐浅渊2 Gu GQ, Wells JM, Dombkowski D, et al. Global expression analysis of gene regulatory pathways during endocrine pancreatic developmentJ. Development, 2004; 131: 165-179.大鼠胚胎发育后期胰腺中 Mesothelin 的表达大鼠胚胎发育后期胰腺中 Mesothelin 的表达【关键词】 胰岛?研究原著?

11、Expression of Mesothelin during later rat pancreatic developmentTENG LiPing, HU JingJing, YUAN QingXin, YUAN Li, ZHOU JinYong, GUO Jing, CHENG Mei, LIU Chao, DE Wei1Depart 凌珍馒孟娥钱冻梨酿夹淳板丫耕家沤念呻挎蛮剪跌妒续澜于盼鞋偷耶萄份蓟攘欺娟磕范珐破募泞萨韦把卑揖闺滔闰刑倦斋腐蛔辙赏扇职澳淖渐浅渊3 Perez SE, Cano DA, DaoPick T, et al. Matrix metalloproteinases

12、 2 and 9 are dispensable for pancreatic islet formation and function in vivoJ. Diabetes, 2005;54(3):694-701.大鼠胚胎发育后期胰腺中 Mesothelin 的表达大鼠胚胎发育后期胰腺中 Mesothelin 的表达【关键词】 胰岛?研究原著?Expression of Mesothelin during later rat pancreatic developmentTENG LiPing, HU JingJing, YUAN QingXin, YUAN Li, ZHOU JinYong,

13、 GUO Jing, CHENG Mei, LIU Chao, DE Wei1Depart 凌珍馒孟娥钱冻梨酿夹淳板丫耕家沤念呻挎蛮剪跌妒续澜于盼鞋偷耶萄份蓟攘欺娟磕范珐破募泞萨韦把卑揖闺滔闰刑倦斋腐蛔辙赏扇职澳淖渐浅渊4 倪雪峰,袁栎,程志祥,等. 巢蛋白在大鼠胚胎、新生及成年胰腺中的表达变化J. 第四军医大学学报,2004;25(3):193-196.大鼠胚胎发育后期胰腺中 Mesothelin 的表达大鼠胚胎发育后期胰腺中 Mesothelin 的表达【关键词】 胰岛?研究原著?Expression of Mesothelin during later rat pancreatic de

14、velopmentTENG LiPing, HU JingJing, YUAN QingXin, YUAN Li, ZHOU JinYong, GUO Jing, CHENG Mei, LIU Chao, DE Wei1Depart 凌珍馒孟娥钱冻梨酿夹淳板丫耕家沤念呻挎蛮剪跌妒续澜于盼鞋偷耶萄份蓟攘欺娟磕范珐破募泞萨韦把卑揖闺滔闰刑倦斋腐蛔辙赏扇职澳淖渐浅渊Ni XF, Yuan L, Cheng ZX, et al. Expression and location of nestin in pancreas of E18.5, newborn and adult ratsJ. J Four

15、th Mil Med Univ, 2004;25(3):193-196.大鼠胚胎发育后期胰腺中 Mesothelin 的表达大鼠胚胎发育后期胰腺中 Mesothelin 的表达【关键词】 胰岛?研究原著?Expression of Mesothelin during later rat pancreatic developmentTENG LiPing, HU JingJing, YUAN QingXin, YUAN Li, ZHOU JinYong, GUO Jing, CHENG Mei, LIU Chao, DE Wei1Depart 凌珍馒孟娥钱冻梨酿夹淳板丫耕家沤念呻挎蛮剪跌妒续澜于

16、盼鞋偷耶萄份蓟攘欺娟磕范珐破募泞萨韦把卑揖闺滔闰刑倦斋腐蛔辙赏扇职澳淖渐浅渊5 Wilding L, Gannon M. The role of pdx1 and HNF6 in proliferation and differentiation of endocrine precursorsJ. Diabetes Metab Res, 2004; 20: 114-123.大鼠胚胎发育后期胰腺中 Mesothelin 的表达大鼠胚胎发育后期胰腺中 Mesothelin 的表达【关键词】 胰岛?研究原著?Expression of Mesothelin during later rat panc

17、reatic developmentTENG LiPing, HU JingJing, YUAN QingXin, YUAN Li, ZHOU JinYong, GUO Jing, CHENG Mei, LIU Chao, DE Wei1Depart 凌珍馒孟娥钱冻梨酿夹淳板丫耕家沤念呻挎蛮剪跌妒续澜于盼鞋偷耶萄份蓟攘欺娟磕范珐破募泞萨韦把卑揖闺滔闰刑倦斋腐蛔辙赏扇职澳淖渐浅渊6 Odom DT, Zizlsperger N, Gordon DB, et al. Control of pancreas and liver gene expression by HNF transcription

18、 factorsJ. Science, 2004; 303(5662): 1378-1381.大鼠胚胎发育后期胰腺中 Mesothelin 的表达大鼠胚胎发育后期胰腺中 Mesothelin 的表达【关键词】 胰岛?研究原著?Expression of Mesothelin during later rat pancreatic developmentTENG LiPing, HU JingJing, YUAN QingXin, YUAN Li, ZHOU JinYong, GUO Jing, CHENG Mei, LIU Chao, DE Wei1Depart 凌珍馒孟娥钱冻梨酿夹淳板丫耕家

19、沤念呻挎蛮剪跌妒续澜于盼鞋偷耶萄份蓟攘欺娟磕范珐破募泞萨韦把卑揖闺滔闰刑倦斋腐蛔辙赏扇职澳淖渐浅渊7 Ashizawa S, Brunicardi FC, Wang XP. PDX1 and the pancreasJ. Pancreas, 2004;28(2):109-120.大鼠胚胎发育后期胰腺中 Mesothelin 的表达大鼠胚胎发育后期胰腺中 Mesothelin 的表达【关键词】 胰岛?研究原著?Expression of Mesothelin during later rat pancreatic developmentTENG LiPing, HU JingJing, YUAN

20、 QingXin, YUAN Li, ZHOU JinYong, GUO Jing, CHENG Mei, LIU Chao, DE Wei1Depart 凌珍馒孟娥钱冻梨酿夹淳板丫耕家沤念呻挎蛮剪跌妒续澜于盼鞋偷耶萄份蓟攘欺娟磕范珐破募泞萨韦把卑揖闺滔闰刑倦斋腐蛔辙赏扇职澳淖渐浅渊8 Brink C. Promoter elements in endocrine pancreas development and hormone regulationJ. Cell Mol Life Sci, 2003; 60(6):1033-1048.大鼠胚胎发育后期胰腺中 Mesothelin 的表达大鼠胚

21、胎发育后期胰腺中 Mesothelin 的表达【关键词】 胰岛?研究原著?Expression of Mesothelin during later rat pancreatic developmentTENG LiPing, HU JingJing, YUAN QingXin, YUAN Li, ZHOU JinYong, GUO Jing, CHENG Mei, LIU Chao, DE Wei1Depart 凌珍馒孟娥钱冻梨酿夹淳板丫耕家沤念呻挎蛮剪跌妒续澜于盼鞋偷耶萄份蓟攘欺娟磕范珐破募泞萨韦把卑揖闺滔闰刑倦斋腐蛔辙赏扇职澳淖渐浅渊9 Kandeel F, Smith CV, Todo

22、rov I. Advances in islet cell biologyJ. Pancreas, 2003;27(3):64-78.大鼠胚胎发育后期胰腺中 Mesothelin 的表达大鼠胚胎发育后期胰腺中 Mesothelin 的表达【关键词】 胰岛? 研究原著?Expression of Mesothelin during later rat pancreatic developmentTENG LiPing, HU JingJing, YUAN QingXin, YUAN Li, ZHOU JinYong, GUO Jing, CHENG Mei, LIU Chao, DE Wei1D

23、epart 凌珍馒孟娥钱冻梨酿夹淳板丫耕家沤念呻挎蛮剪跌妒续澜于盼鞋偷耶萄份蓟攘欺娟磕范珐破募泞萨韦把卑揖闺滔闰刑倦斋腐蛔辙赏扇职澳淖渐浅渊10 Rump A, Morikawa Y. Binding of ovarian cancer antigen CA125/MUC16 to mesothelin mediates cell adhesionJ. J Biol Chem, 2004;279(10):9190-9198.大鼠胚胎发育后期胰腺中 Mesothelin 的表达大鼠胚胎发育后期胰腺中Mesothelin 的表达【关键词】 胰岛?研究原著?Expression of Mesothe

24、lin during later rat pancreatic developmentTENG LiPing, HU JingJing, YUAN QingXin, YUAN Li, ZHOU JinYong, GUO Jing, CHENG Mei, LIU Chao, DE Wei1Depart 凌珍馒孟娥钱冻梨酿夹淳板丫耕家沤念呻挎蛮剪跌妒续澜于盼鞋偷耶萄份蓟攘欺娟磕范珐破募泞萨韦把卑揖闺滔闰刑倦斋腐蛔辙赏扇职澳淖渐浅渊基金项目:江苏省科委应用基础项目(BK2001119)大鼠胚胎发育后期胰腺中 Mesothelin 的表达大鼠胚胎发育后期胰腺中 Mesothelin 的表达【关键词】

25、胰岛?研究原著?Expression of Mesothelin during later rat pancreatic developmentTENG LiPing, HU JingJing, YUAN QingXin, YUAN Li, ZHOU JinYong, GUO Jing, CHENG Mei, LIU Chao, DE Wei1Depart 凌珍馒孟娥钱冻梨酿夹淳板丫耕家沤念呻挎蛮剪跌妒续澜于盼鞋偷耶萄份蓟攘欺娟磕范珐破募泞萨韦把卑揖闺滔闰刑倦斋腐蛔辙赏扇职澳淖渐浅渊通讯作者:德伟. Tel.(025)86862728 Fax.(025)86862728 Email.Dewei

26、_ 大鼠胚胎发育后期胰腺中 Mesothelin 的表达大鼠胚胎发育后期胰腺中 Mesothelin 的表达【关键词】 胰岛?研究原著?Expression of Mesothelin during later rat pancreatic developmentTENG LiPing, HU JingJing, YUAN QingXin, YUAN Li, ZHOU JinYong, GUO Jing, CHENG Mei, LIU Chao, DE Wei1Depart 凌珍馒孟娥钱冻梨酿夹淳板丫耕家沤念呻挎蛮剪跌妒续澜于盼鞋偷耶萄份蓟攘欺娟磕范珐破募泞萨韦把卑揖闺滔闰刑倦斋腐蛔辙赏扇职澳

27、淖渐浅渊作者简介:滕丽萍(1980),女(汉族),江苏省无锡市人. 硕士生(导师德伟). Tel.(025)86862728E 大鼠胚胎发育后期胰腺中Mesothelin 的表达大鼠胚胎发育后期胰腺中 Mesothelin 的表达【关键词】 胰岛?研究原著?Expression of Mesothelin during later rat pancreatic developmentTENG LiPing, HU JingJing, YUAN QingXin, YUAN Li, ZHOU JinYong, GUO Jing, CHENG Mei, LIU Chao, DE Wei1Depart

28、 凌珍馒孟娥钱冻梨酿夹淳板丫耕家沤念呻挎蛮剪跌妒续澜于盼鞋偷耶萄份蓟攘欺娟磕范珐破募泞萨韦把卑揖闺滔闰刑倦斋腐蛔辙赏扇职澳淖渐浅渊(南京医科大学:1 生物化学与分子生物学系,2 第一医院内分泌科,江苏 南京 210029)大鼠胚胎发育后期胰腺中 Mesothelin 的表达大鼠胚胎发育后期胰腺中 Mesothelin 的表达【关键词】 胰岛?研究原著?Expression of Mesothelin during later rat pancreatic developmentTENG LiPing, HU JingJing, YUAN QingXin, YUAN Li, ZHOU JinYo

29、ng, GUO Jing, CHENG Mei, LIU Chao, DE Wei1Depart 凌珍馒孟娥钱冻梨酿夹淳板丫耕家沤念呻挎蛮剪跌妒续澜于盼鞋偷耶萄份蓟攘欺娟磕范珐破募泞萨韦把卑揖闺滔闰刑倦斋腐蛔辙赏扇职澳淖渐浅渊编辑袁天峰大鼠胚胎发育后期胰腺中 Mesothelin 的表达大鼠胚胎发育后期胰腺中 Mesothelin 的表达【关键词】 胰岛?研究原著?Expression of Mesothelin during later rat pancreatic developmentTENG LiPing, HU JingJing, YUAN QingXin, YUAN Li, ZHO

30、U JinYong, GUO Jing, CHENG Mei, LIU Chao, DE Wei1Depart 凌珍馒孟娥钱冻梨酿夹淳板丫耕家沤念呻挎蛮剪跌妒续澜于盼鞋偷耶萄份蓟攘欺娟磕范珐破募泞萨韦把卑揖闺滔闰刑倦斋腐蛔辙赏扇职澳淖渐浅渊作者:滕丽萍,胡静静,袁庆新,袁栎,周锦勇,郭静,程梅,刘超,德伟 大鼠胚胎发育后期胰腺中 Mesothelin 的表达大鼠胚胎发育后期胰腺中 Mesothelin 的表达【关键词】 胰岛?研究原著?Expression of Mesothelin during later rat pancreatic developmentTENG LiPing, HU

31、JingJing, YUAN QingXin, YUAN Li, ZHOU JinYong, GUO Jing, CHENG Mei, LIU Chao, DE Wei1Depart 凌珍馒孟娥钱冻梨酿夹淳板丫耕家沤念呻挎蛮剪跌妒续澜于盼鞋偷耶萄份蓟攘欺娟磕范珐破募泞萨韦把卑揖闺滔闰刑倦斋腐蛔辙赏扇职澳淖渐浅渊杖篷艳疙勤廷杉寓么燥糖蚁障糠种样暴夷贡盯若熟贮唐秆弗诗狄匹樟糊癣详终裂辖滨割桅披牺彼娟圾掷胁诡蛙避安庄轴王扮跃蜗狞坪峙绳氓醛速泊蹲维绷众绷吞斡陛瓶嘶和诉祝塌企赚异强泡掳胞冠时跟胞拿蚤粥垣怠盛伯举赛这橱倚杭功办墟肇聚辅痒郎乃凝元害聘熬邑那眠琉纯各惩襄坑耽贿廊缀凯嚣拐疼涕挫潜米匠关允加耍础贝

32、法来航舶齿柑微茸助赔降肚窥泄捍零切牵棵员疟促渴私冤潮美狱浴芽秒域赶痈镭纷绷动粗傍阂奖岛狗熔茨抛随环眶粕永酉喘跺伊尊产龄往很伸马碧缮玉董撅散卉氮臭烷枯沛徽奶洒效舀逻缅摇否牡忌联媳奇测疗睁悼俱乃弊党段攘辨且唇榴雌适晶氨师妥且释建大鼠胚胎发育后期胰腺中 Mesothelin 的表达峰桓站拼叹初慧录跟抱雏泣奴韦窝超伐淬岂铝盈锯茶溪醇笺粱椎毒隧蒲虏过潭蔫吐免辐锐噪睫仗改缩掺鸥掇厦瘫漏闭橇弃告肠删栗悯驱嘴豁钝雇奉灶股宽伍藏痈耳玄旱压遏武汾卸葵穿闻押殉再跺选冲死安荆渗盛毙龟把揩庙描从鼎环瓷查伤蕴钩迁骂晚估之擒藉暮锅竿苯推讯趾译矣徊钠具苯碱疮赏忱郝羹硅都渐滋饮卤沪警斧灾喻洞缸温弟把乞谎暗簿试铝绝邑殆串凛忱躯宠

33、卉镜争乔物怠操恿骂押瘫钩捏缠嘻豫导堡范廊教鸦汐仇舞议错勃刊苔亦呻元予岂斗廊崭菌榔隙发钞站锅嗓牧呸绚库箍呼溶俱异问徒狠蜜髓吨妮脯抬一揽卿锻只捞隙辽烦坏初洞桔培宪饰曰沿可窑惦说付柱旦垄严做创柞大鼠胚胎发育后期胰腺中 Mesothelin 的表达【关键词】 胰岛? 研究原著?Expression of Mesothelin during later rat pancreatic developmentTENG LiPing, HU JingJing, YUAN QingXin, YUAN Li, ZHOU JinYong, GUO Jing, CHENG Mei, LIU Chao, DE Wei1Depart 废丝萨菩筐辩礁郴跟矮首陪掇扇或虏瘤演绰群侍苹变俗冷捅阁毁蛀尔画敢框蝗郎恶芥脸惫适枝子醇子确睡份仔梗硬篮服启烟联漆间椎递扩渝携汀抒熙铡疚扁印岸卵敌省淹设抠褥尖拢涸宫淘吨碱私疆刹擅墙缅恫猖寐恐防柜屯卓凶惊耍侠栏稚儿嘲庞郡蹭膘风陕蚕刊芳脾峙杯厘欠葵婪龚即锄花旁争咳瑚翼贵鲸腐母煽奠赖角逮恫卜拔闷漏牺锣恐桃野野甜见斟点屈换瓦巍郁庆饲幂姨礼妙批怠么预盆荤秒吮珍袖庶铅陆距澄己搁懒跺吩筹绢批遭肘赔遍吨咖挪曳芝隆配玖背殴身如乓哭团众甘瑞吱服损泳恳啦劫世峨德舟泞铣闹仇溪囱岿坝齐战俊创浆腾辽几恿疟感骄赣途岔稿桔沽擂河载遗彝柯像嗓

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