1、生育 期 HPV感染抗病毒策略This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 m
2、icrocontroller and DS18B20 temperature sensor.主要内容 HPV的研究历程 HPV病毒学基础知识 HPV感染 对 机体的 影响 HPV检测方法 HPV感染预防 HPV感染治疗This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature
3、 sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.HPV的研究历程 上世纪 70年代末， Harald zur Hausen 首先提出人乳头瘤病毒 (Human papilloma virus HPV)可能是宫颈癌的致癌病毒。This paper mainly introduces the design of an intelligent temperature co
4、ntrol system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.v1977年， Laverty在电镜中观察到宫颈癌活检组织中存在人乳头瘤病毒颗粒
5、；(Laverty CR, et al., Adenovirus infection of the cervix , Acta Cytol, 1977, 21(1): 114-117)HPV的研究历程 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor
6、DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor. 1989年左右， Keerti Shah等发现 99.7%的宫颈癌与 HPV感染有关 ，证实了宫颈癌与HPV感染有直接关系。（ Muoz N, et al., The causal link between HPV and invasive cervical cancera population-based case-control
7、 study in Colombia and Spain, Int. J. Cancer, 1992, 525:743-749）HPV的研究历程 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip micr
8、ocomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor. 1995年，国际癌症研究机构 (IARC)专题讨论会通过 HPV感染是宫颈癌的主要原因； 2005年， IARC/WHO推荐 HPV检测可以用于宫颈癌筛查；HPV的研究历程 This paper mainly introduces the design of an intelligent temperature control system which realizes the func
9、tion of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.HPV的研究历程 2008年 10月 6日公布 Harald zur Hausen获诺贝尔生理学或医学奖。This paper mainly introd
10、uces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature
11、sensor.在 “ 诺奖 ” 评审委员会发布的新闻公告中，这样写道， “ 拉尔德 楚尔 豪森敢于摒弃教条，他所做出的探索性工作，让人类了解了 HPV与宫颈癌的关系，促进了针对 HPV疫苗的开发 ” 。 宫颈癌也由此可能成为人类通过注射疫苗、筛查和早诊早治来预防，并被消除的第一个恶性肿瘤。 唯一病因 明确，唯一 可以早期预防和 治疗，唯一可以彻底根除的 癌症。HPV的研究历程 This paper mainly introduces the design of an intelligent temperature control system which realizes the functi
12、on of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.病毒学基础知识This paper mainly introduces the design of an intelligent temperature co
13、ntrol system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.病毒学基础知识 小双链环状 DNA病毒 基因组长约 8Kb 直径 5055nm，由
14、 72个病毒壳粒包被 嗜上皮性和较高的种依赖性 自然界中呈裸核休眠状态，生存能力强。This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components
15、of the system are AT89C51 microcontroller and DS18B20 temperature sensor.病毒学基础知识 目前世界上已发现的 110 余种 HPV,大约 35种型别涉及生殖道感染， 约 20种与肿瘤有关 。根据不同型别 HPV与癌发生的危险性高低分为高危型和低危型 2种。This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurem
16、ent and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.危险性 型别 引起疾病高危型高危型HPV16 ,18 ,31 ,33 ,35 ,39 ,45 51 ,52 ,56 ,58 ,59 ,68 ,73 ,82 等高度子宫颈上皮内瘤样变(CIN 、 ) 和宫颈癌低危
17、型 HPV6 ,11 ,40 ,42 ,43 ,44 ,54 ,61 ,70 ,72 ,81 ,cp6108 等 生殖道尤其是阴道下部及肛周皮肤的湿疣类病变和低度子宫颈上皮内瘤样变 (CIN ) 病毒学基础知识This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sen
18、sor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.病毒学基础知识八个基因 , 根据上皮分化阶段的早、晚分别命名为早期基因（ E）和晚期基因（ L） E1, E2, E5, E6 和 E7 在上皮分化的早期阶段就能表达 , E4 可在上皮分化的整个过程中表达 . 它们调控病毒的转录和复制 ,并作用于宿主的基因组This paper mainly introduces the d
19、esign of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.HPV
20、16nL1: 主要衣壳蛋白，是疫苗的主要成分 L2: 次要衣壳蛋白，是市售抗体的主要识别位点E4：结合并破坏细胞角蛋白网，形成挖空细胞的外观E2：负性调节E6和 E7，维持凋亡和细胞周期的调控。通常在病毒发生整合（病毒整合时会破坏 E2基因的结构）时失活HPV 的主要致癌基因n E6 通过抑制 p53而阻断凋亡n E7 通过抑制 pRB使细胞周期失控XThis paper mainly introduces the design of an intelligent temperature control system which realizes the function of tempera
21、ture measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.E655:74108. 2. World Health Organization. Geneva, Switzerland: World Health Organization; 19
22、99:122. 3. World Health Organization. WHO Office of Information. WHO Features. 1990;152:16.非致癌HPV类型This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS
23、18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.SIL = Squamous intraepithelial lesion - CIN : Cervical intraepithelial neoplasiaHPV感染与子宫颈癌发生发展的自然史This paper mainly introduces the design of an intelligent temperature co
24、ntrol system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.HPV主要检测方法 1.PCR-HPV 2.HC-2 3.原位杂交This pap
25、er mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.HPV基因分型检测试剂盒操作步骤
