1、paragonimus,Typical character,Female genital system:,Ovary and womb are at the same level on midline,male genital system:,Testes are located at the junction of the posterior fourth of the body,The main parasite including:,1. Paragonimus westermani,2. Pagumogonimus skrjabini,Paragonimus westermani,mo
2、rphology,1.adult,2. egg,Live cycle,Adult,egg,Eggs pass into water in feces,miracidium,Mather sporocyst,Son sporocyst,cercaria,All these stage are,growed in the snail,Cercaria leave snail and are eated By crab in the small stream,metacercaria,Man is infective by eating the raw crab .the metacercaria
3、Are hatched in the duodenum,worm,Worm move through The internal organs,adult,Worms moving way:,Small intestine,Abdominal cavity,Thoracic cavity,lung,Pass the diaphragmatic surface,Attention:,1. Ectopic parasitism,Brain ,spinal cord, subcutaneous,liver,eye,Transport host:,Some parasite worm invade ab
4、normal host ,it can not become adult,it maintain the worm stage,but when it has chance to invade normal host it become adult ,the abnormal host called it.,Pathogenesis and clinical manifestation,1. Acute period (cause by young worm),The young worms activity cause the partial tissue and organ damaged
5、,bleed,inflamation,the damaged area became a hole and then lead to the tissue fibous,adhesions,particularly the liver.,2.chronic period,Pathogenesis in lung,The adults mechanical spoil And its secretion and excretion,inflammation,abscess,cyst,When the adult die or move Other place or the content Rem
6、ove or absorbed,Granulation tissue formed,fibrous,Clinical symptom,The patient feel chest discomfort cough ,hemoptysis , Sputum is brown-flake, egg is often found in the sputum,B. Ectopec parasitism,Brain-brain discomfort ,epilepsy,paralysis,Spinal cord-paresis,Subcutaneous-cysts in the skin,Eye -lo
7、se sight or vision disorder,Peritoneum-abdominal pain ,diarrhea,blood-stood,enlarging liver,Lungsymptom,Diagnosis,Make sure whether the patient has the habit Of eating the raw crab,1. examination,Use the water sedimentation method tofind the egg in the feces,Use the direct smear method to find the e
8、gg in the sputum,2. X-ray ,CTfor the pleura and brain-spinal cords patient,3.immuniology examination,For the ectopic parasitism,Method: AST,ELISA,AST-ELISA,Epidemiology,Charcteristic: parasitic zoonoses,Paragonimiasis infect the wile animalin the nature,when human being come into the area he will be
9、 infect.,Paragonimiasis had ever taken place in Japan ,Korea, Russia,Epidimiology factors:,1.infective source:,A.Wild animal :fox, wolf, leopard,cat dog etc.,B.human being,2. Intermediate host :the snail or the crab which grow in the small stream.,3.infective way:,A.eat the raw crab or “drunk crab”,
10、B.drink the unboiling water,Treatment,Pay attention to the eating habit ,not to eat the raw crab,not to drink the unboiling water,2. Treat the patient:,Pagumogonimus skrjabini,morphology,1. adult,Shape :olive,Sucker:ventral sucker is larger than oral sucker,Testes and ovary have more lobation,2. egg
11、: similar to paragonimus westermuni,Live cycle,Essential similar to paragonimus westermuni,The different from it is that:,1. Definitive host: fruit-eating fox (the main),Human : abnormal host ,only young worm infectthem.,2.the No.1 intermediate host:The snail which grow in the small stream,Pathogene
12、sis and clinical manifestations:,1. larva migrans: some parasite invade human being , human is not the normal host ,it only stay in the stage of young worm ,the young worm paraste and migration in the body for a long time ,at last it cause particular and peneral pathologic change.,Clinical symptom:,1.subcutaneous type: cysts,Area: back and abdomen, four limbs, inguinal region, head and neck,2. Internal organ:differ from what it invade the organ,Diagnosis,1. Operation:,2. Blood examination:,3. Immunologic test,Epidemiology and treatment,Similar to paragonimus,