1、 ( ) 2013 4 -2016 8 116 , 58 , 2 20min ; 2 , 2 , (P0.05) 20min , , (P0.05) 20min , , (P0.05) , 1.2 : (1) ; (2) ; (3) , : (1) ; (2) 1.3 : 2 0.1g 0.5 mg , ; : (1) 2 (2mg/kg) (0.2mg/kg) , (2) (34 mg/h) ( 0.6%1.3%) ; : 23h 57 mL 0.375% , (23 mg/h) ( 0.4%0.6%) 1.4 (1) 2 20min (2) 2 (3) 2 1.5 SPSS 17.0 ,
2、t , P0.05) 20 min , /min, /min /min, 0) /min /min, (P0.05) 20min , (P0.05) ( 2) 2.3 2 mg (P0.05) ( 3) 2.4 2 , (P0.05) ( 4) 1 2 20min /min) 2 2 20min 3 2 4 2 3 7-10, , , 11-13 , 14-16 , 20min , , , 17-18, , ; , , , , 19-20 , , , , , 1 . J. , 2016, 35 (11) :108-109.DOI:10.16662/ki.1674-0742.2016.11.10
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