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类型健儿止泻颗粒联合蒙脱石散治疗小儿腹泻的临床研究.doc

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    1、 2015 6 2017 3 102 , , 51 , 1 :1/3 / , 1 3 :1/2 / , :1 / , 3 /d , 1 :6 g/ , 1 5 :6 1 2 g/ , :12 1 8 g/ , 3 /d 7 d , , 92.16% 100.00%, (P0.05) , , (P0.05) , A (Ig A) G (Ig G) CD 4+ /CD 8+ , (P0.05) ; , (P0.05) , , , , ; ; ; ; ; . , , , Tel:15909912861E-mail: Clinical study on Jianer Zhixie Granules c

    2、ombined with Montmorillonite Powder in treatment of infantile diarrhea HALIMULATI Maiwulidan YASEN Yalikun KARI Adilijiang YIMINGJIANG Mubalake Department of Pharmacy, the First Affiliated Hospital of Xinjiang Medical University; Department of Cardiology, Xinjiang Cardiovascular and Cerebrovascular

    3、Disease Hospital; Department of Pediatrics, the First Affiliated Hospital of Xinjiang Medical University; Department of Chemistry and Pharmacy, College of Pharmacy, Xinjiang Medical University; Abstract Objective To explore the clinical efficacy of Jianer Zhixie Granules combined with Montmorillonit

    4、e Powder in treatment of infantile diarrhea. Methods Children (102 cases) with diarrhea in the First Affiliated Hospital of Xinjiang Medical University from June 2015 to March 2017 were randomly divided into control and treatment groups, and each group had 51 cases. Children in the control group wer

    5、e po administered with the treatment group were po administered with Jianer Zhixie Granules on 5 years: 6 18 g/time, three times daily. Patients in two groups were treated for 7 d. After treatment, the clinical efficacies were evaluated, and the time of symptom improvement and the immune function in

    6、dexes in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 92.16% and 100.00%, respectively, and there was difference between two groups (P 0.05) . After treatment, antidiarrheal time, antiemetic time, the time of abdominal pain impro

    7、vement, antipyretic time, and dehydration correction time in the treatment group were significantly shorter than those in the control group, and there was difference between two groups (P 0.05) . After treatment, the levels of Ig A, Ig G, and CD4+/CD8+ in two groups were significantly increased, and

    8、 the difference was statistically significant in the same group (P 0.05) . And the observational indexes in the treatment group were significantly higher than those in the control group, with significant difference between two groups (P 0.05) . Conclusion Jianer Zhixie Granules combined with Montmor

    9、illonite Powder has clinical curative effect in treatment of infantile diarrhea, can improve clinical symptoms, and regulate immune function indexes, with good safety, which has a certain clinical application value. Keyword Jianer Zhixie Granules; Montmorillonite Powder; infantile diarrhea; symptom

    10、improvement time; immune function; , , , , 1 12 , 68 , , 68 , 2 3 , , , 4 , 1 1.1 2015 6 2017 3 102 62 , 40 ; 5 10 , ; 124 h, 5 : ; ; : ; ; ; 10 d ; 1.2 , 51 30 , 21 ; 5 9 , ; 124 h, 32 , 19 ; 5 10 , ; 224 h, , , , ( ) , 3 g/ , M06534, 1 :1/3 / , 13 :1/2 / , :1 / , 3 /d ( ) , 6 g/ , 1509056, 1 :6 g/

    11、 , 15 :612 g/ , :1218 g/ , 3 /d 7 d , , 1.3 5 : , ; : , , ; : , 1.4 1.4.1 , 1.4.2 , A (Ig A) G (Ig G) , CD CD , CD/CD 1.5 , 1.6 SPSS 20.0 , , , t 2 2.1 , 36 , 11 , 92.16%; 45 , 6 , 100.00%, (P0.05) , 1 2.2 , , (P0.05) , 2 2.3 , Ig A Ig G CD/CD , (P0.05) ; , (P0.05) , 3 1 Table 1 Comparison on clinic

    12、al efficacies between two groups 2 n on the time 3 2.4 , 1 , 1.96%; 1 , 1 , 3.92%, 3 , , , , , , , , , , , , , , , , , 6-7 , , , , , , , , , , , , , 8 , 92.00%, , , , 9 , , , , , , , , 10 , , , , , , , , , 100.00%, 92.16%, ; , , , , CD CD , 11, Ig A Ig G , 12 CD/CD Ig A Ig G , 3.92%, 1.96%, , , , ,

    13、, , , , 1 , , , . J. , 2017, 12 (10) :7-9. 2 , . J. , 2016, 22 (19) :2339-2342. 3 . J. , 2017, 4 (16) :3097-3098. 4 , , , . J. , 2006, 17 (8) :1506-1507. 5 . J. , 1998, 13 (6) :381-384. 6 . J. , 2016, 32 (16) :1464-1467. 7 , , , . J. , 2016, 36 (12) :167-169. 8 . J. , 2016, 21 (3) :394-396. 9 . J. , 2015, 31 (z1) :76. 10 , . J. , 2011, 7 (1) :59-64. 11 , . J. , 2007, 29 (4) :502. 12 , , , . J. , 1995, 21 (6) :363-365.

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