1、 , , , ; ; ; ; (1983 ) , , , , , Research Advances on Extraction Method and Physiological Functions of Codonopsis Polysaccharide PEI Xiao-ping ZHENG Qian-min Department of Food Abstract Codonopsis is a famous and precious traditional Chinese herbal medicinal, with the function of tonifying middle-Ji
2、ao and Qi and strengthening spleen and tonifying lung and other effects. Polysaccharide is one of the functional components of codonopsis. In this assay, the extraction methods, physiological functions, development application and their future development prospects was briefly summarized, to offer t
3、heoretical basis for the depth development of codonopsis. Keyword Codonopsis polysaccharide; Extraction methods; Physiological functions; Development and application; 2005 , , 40 , 39 , 21 , 1, , 2 , 1 1.1 3 : 3 , 1 h, 1 10 , 2 3 8 ; 1 g ( ) /m L, 80%, 24 h 4 , 2 h, 100 g 500 m L , 250 m L, 1 h , ,
4、; , 80% 250 m L 2 , 1.5 h, , 500 m L 1 h 40 min, , 250 m L 30 min, , , 75 m L, , 43.6% 5 , 1 h, 3 , 34.5% 6 40 g, 400 m L , 3 , 2 h, , 3 , 1/5, 3 95% , , 4 000 r/min , , , 1.095 g 7 , : 1.0 h, 3 , 1 g/m L, 80%, 26.45% 8 , 2 h, 3 h, 26.45% 9 : 2 h; 95% 2 h; 10 ; sevage , 80%, 12 h, ; 10% 10 , , , , ,
5、 4 h, , , 8.50% , , , , , 1.2 11 : 600 W 50 min, , 15.9%, 28.36%; 8.27%, 18.17%, 12 - , : 60 , 80% , , 700 W 45 min 2 , 13.57% 13 : 20 min 3 , 24.59% , , , , , 1.3 14 , : 45 min, 195.1 mg/g; 78.22 mg/g , , , ( ) 3 : (1) , , , ; (2) , , , ; (3) , 1.4 15 , : 130 W, 6 min, 3 , 15.79%, 15.11% , , , 16 ,
6、 : 390 W 6 min 2 , 14.82%; 10.26%, , , ; , , , 1.5 17 , : 90 min, 2.4%, , , 23.92%, , 18 , , 60 U/g 90 min p H 5.0 23.73%; 120 U/g 150 min p H 4.0 28.22% 19 ( + + ) , : 90 90 150 U/g , p H 5.0 90 min, 26.47% 2 2.1 20 D- , (SOD) (ATP) , , , ; D- (MDA) (LF) , , ; (HYP) , , , 21 , , MDA SOD , LF , (GSH
7、-Px) (NOS) , , 22 , SOD , MDA ; (O2 (IC50) 2.2 23 , S180 17.7%, , 68.8%, 44.0%, 24 , 0.5 1.0 2.0 g/kg S180 15% 35% 54%, , S180 25 , HCT116 , TRAIL HCT116 26 , SMMC-7721 , SMMC-7721 , , , SMMC-7721 27 , , S180 34.29%, 2.3 28-29 , , , ( , P0.01 P0.05) , ; ( Y ) ( ) 40% ( ) , (P0.01 P0.05) , , (P0.01)
8、; 40% (P0.01 P0.05) , (P0.01) 2.4 30 (CTX) , , , , CTX 31 (CPPS) (s CPPS5) CTX , , , CY (P0.05) ; CPPS s CPPS5 , CPPS CPPS, 32 , (SR-BC) , 2.5 33 34 2, 4, 6- (TNBS) , , , , , , TNBS 35 5- (5-FU) , , 5-FU / (P0.01) , 5-FU 2.6 36 , , 37 , , , , , , 2.7 38 , , , , , (P0.05) , 39 , , 2.8 40 , , , , , 3
9、3.1 41 , : , 2.19 , 12 40 min 2 , 1 h, , 4 m L 1 g , , 20% , 10 min, , 24 h, , , 16% 1.44% , 2530 min , 42-43 , , : 2 g 100 m L , 2 mol/L Ca Cl2 100 m L, 2 mol/L Ca Cl2 , 2 mol/L Na OH p H 911, , , 1 h, ; 24 h, , ; , , : 2 g 0.5 g, 60 m L , , ; 5 min, 20% p H 8.08.5, 2 mol/L , , p H 8.08.5, , , 1 h, , , 3.2 44 , : PEG4000 PEG6000 30 d/min, 20 cm, , 2 mm, 25 mg; , , , 100 m L/ (2 g /m L) , , 45 46 , : 10%, PVP 10%, 0.3%; , 4 , ,
