1、BORDETELLA,K.V.PRAVEEN CHANDER,Important species,Bordetella pertussis - Bordet-Gengou bacillus Bordetella parapertussis Bordetlla bronchiseptica - ancestral formBordetella avium -causes respiratory disease in turkeys,Virulence,Steele, R.W. Pertussis: Is Eradication Achievable. Pediatric Annals. Aug
2、2004. 33(8):525-534,Adhesions,Filamentous hemagglutinin Pertactin Fimbriae,http:/www.rivm.nl/infectieziektenbulletin/bul1306/kinkhoest.jpg,http:/www.my-pharm.ac.jp/yishibas/research/Pertussis1.jpg,Toxins,Pertussis Toxin Adenylate Cyclase Toxin Tracheal cytotoxin Dermonecrotic toxin Heat-labile toxin
3、,www.ibl.fr/u447/u447.htm,Pertactin,Outer membrane protein antigen present in all virulent strainsIncluded in acellular pertussis vaccine,Bordetella parapertussis,Infrequent, cause of whooping cough Disease is mild Pertussis vaccine do not give protection,Bordetella bronchiseptica,Peritrichate flagella Antigenetically related to pertussis and abortus Occurs naturally in the respiratory tract of several sps of animals,THANK YOU,