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t细胞免疫ppt课件.pptx

1、This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller

2、and DS18B20 temperature sensor.第十二章T淋巴细胞介导的细胞免疫应答1This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core com

3、ponents of the system are AT89C51 microcontroller and DS18B20 temperature sensor.细胞免疫应答T细胞 识别 抗原效应性 T细胞的 产生 及 效应T细胞 活化 、 增殖 和 分化细胞免疫应答2This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using sing

4、le bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.1 T细胞特异性识别抗原3This paper mainly introduces the design of an intelligent temperature control system which realizes the function of tempe

5、rature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.4This paper mainly introduces the design of an intelligent temperature control system whic

6、h realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.第一节 T细胞识别抗原 MHC的限制性 : TCR在特异性识别 APC所提呈的抗原多肽的过程中,必须同时识别与抗原多

7、肽形成复合物的 MHC分子。APC向 T细胞提呈抗原外 源性抗原内 源性抗原MHC 类分子复合物提呈给CD4+T细胞识别MHC 类分子复合物提呈给CD8+T细胞识别5This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single

8、 chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.第一节 T细胞识别抗原6This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus di

9、gital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.第一节 T细胞识别抗原酪氨酸: Tyr7This paper mainly introduces the design of an intelligent temperature control system which realizes the function of tempera

10、ture measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.第一节 T细胞识别抗原 T细胞利用表面的黏附分子( LFA-1、 CD2) 与 APC表面相应配体( ICAM-1、 LFA-3)结合,促进和增强 T细胞表面 TCR特异性识别和结合抗

11、原肽的能力,这种结合是可逆而短暂的。 T细胞与 APC的非特异结合8This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the s

12、ystem are AT89C51 microcontroller and DS18B20 temperature sensor.第一节 T细胞识别抗原1. TCR识别特异性抗原肽 -MHC分子复合物;2. CD3分子传递特异性抗原刺激信号;3. CD4和 CD8分子分别识别和结合 MHC 类分子和 MHC 类分子,增强 TCR与抗原肽 -MHC分子复合物结合的亲和力;4. 协同刺激分子受配体的结合,有助于维持和加强 T细胞与 APC的直接接触,并为 T细胞激活进一步提供协同刺激信号。 T细胞与 APC的特异性结合9This paper mainly introduces the design

13、 of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.Intercel

14、lular adhesion moleculeLymphocyte functional associated antigen10This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcompute

15、r. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.11This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS1

16、8B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.12This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single b

17、us digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.SMAC: supra-molecular activation cluster 多分子激活聚集体13This paper mainly introduces the design of an intelligent temperature control system wh

18、ich realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.2 T细胞的活化、增殖与分化14This paper mainly introduces the design

19、of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.第二节 T细胞的活

20、化、增殖与分化T细胞活化的第一信号: TCR特异性识别结合在 MHC分子槽中的抗原肽;T细胞活化的第二信号:协同刺激信号( CD28/B7);细胞因子促进 T细胞充分活化: IL-1、 IL-2、 IL-12等。1. T细胞活化涉及的分子15This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital

21、 temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.16This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and co

22、ntrol by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.TCR胞质区较短,须借助 CD3/4/8/28等分子的辅助,才能将抗原刺激的信号传递至细胞内,活化转录因子,转位至核内,活化相关基因,这一过程称为 T细胞活化的信号转导。17This paper mainly introduces

23、 the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sens

24、or.18This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontro

25、ller and DS18B20 temperature sensor.1.T细胞信号转导的原理和一些主要成分 蛋白激酶和蛋白磷酸酶与胞膜相连, Lck、 Fyn游离于胞质, ZAP-70、 SykSH : Src homologyPH: Pleckstrin homologyAkt、 Itk19This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control

26、 by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.1.T细胞信号转导的原理和一些主要成分 SH2、 PH类激活原理ITAM(免疫受体酪氨酸激活基序):20Immunoreceptor tyrosine-based activation motifThis paper mainly intr

27、oduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperatur

28、e sensor.1.T细胞信号转导的原理和一些主要成分CD45在信号转导中的作用21This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components

29、 of the system are AT89C51 microcontroller and DS18B20 temperature sensor.22This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip m

30、icrocomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.DAG : diacylglycerolGRP:Guanosine release proteinPKC:丝苏氨酸激酶CARMA:衔接蛋白激活MAPKKKMAPKKMAPK23This paper mainly introduces the design of an intelligent temperature control system which realizes the f

31、unction of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.基因转录Lck和 Fyn蛋白活化CD3链酪氨酸磷酸化ZAP-70激活磷脂酶 C(PLC) 链磷酸化 生长因子受体结合蛋白 -2( GRB-2)活化二

32、磷酸磷脂酰肌醇( PIP2)水解 m-SOS活化三磷酸肌醇( IP3)水解 甘油二酯( DAG)蛋白激酶( PKC)转录因子活化胞内 Ca+浓度升高钙调磷酸酶Ras-GDP(失活状态)Ras-GTP(激活状态)raf蛋白活化MAP激酶活化DAG-RasGRP24This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single b

33、us digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.T细胞信号转导抑制剂25This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperatur

34、e measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.T细胞激活的其他信号CD28共刺激受体介导的信号转导26This paper mainly introduces the design of an intelligent temperatu

35、re control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.T细胞激活的其他信号 CD28共刺激受体介导的信号转导据报道, CD28

36、传递的信号可使 IL-2 mRNA趋于稳定,使 T细胞分泌 IL-2的数量提高 100倍。27This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core compon

37、ents of the system are AT89C51 microcontroller and DS18B20 temperature sensor.第二节 T细胞的活化、增殖与分化 细胞因子基因: IL-2 细胞因子受体基因 细胞原癌基因 黏附分子基因 MHC3. T细胞信号涉及的靶基因28This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and contro

38、l by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.Jak-ATAT参与细胞因子受体介导的信号转导29This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer. The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.T细胞信号转导的主要转录因子30

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