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动脉栓塞微球的研究进展.doc

1、动脉栓塞微球的研究进展984984984?+?+?k?d?ChineseMedicineModernDistanceEducationofChina?x6?x08?52008?08?e?s?u?T?,?s?i?u?g?0?k?Tg8?u?T?k?v?w?7?g8?v?S?c?1?v?S?v?w?g8?u?:?Y?p?s?S?c?1?s?u?a?U?0?Hg8?u?:?Y?f?,1,2g8?f?4?0?c?s?g9?8?H?g8?u?U?4?x?U?c?u?o?c?c?U?D?O30?8004?m?o?3g8?x?k?O?u?4?i?r?Hg9?i?g81?s?u?H?S?Hg?g?s?u?H?

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4、0?:?n?m?s?.?r?4?eMMC.fGMS?s?c?v?e60.76?9.6?s4?m?c?H?9?D?f?4?0?c?U?F?e?dg8?4?r?i?r?c?r?4?t?n?J?s?i?T?D?s?c?+?U?i?J?w?g83.1.2?4?H?:?n?4?s?S?,?w?h?w?h?g8?T?v?t?t?i,?,?5?,?r,?r?z?U?g8?d?7?:?n?54.04?m?5.fFU?4?c?0?s?u?r?c?o?c?i?p?s?w?c?c?HHPLC?5.fFU?e?l?sg8?r?e5.fFU?C?s?c?5.fFU?4?F?c?w?5.fFU?U?U?c?w?+5.fF

5、U?c?)?S?v?s?c?c?a?Hg83.1.3?4?v?c?:?t?4?o?g9?5?c?c?f?c?t?x?c?H?r?o?,?H?5?R?Ug8?4?u?c?8?H?,?A?o?u?g8?:?n?c?0?0?c?H?s?u?o?4?o?vSpherexg8?H?4?s?u?s?S?D?c?T?H.3?8?4+?0?Y.m?s?N?T?4?u?g8?%?8?P?H?.f?4?u?s?r?c?H?V?:?i?w?g9?g9?+?c?r?u?r?w?r?z?U?eP0.05?s?c?+?r?z?a?eP0.05?sg8?r?4?v?F?0?H?vg9?U?g8Taguchi9?H?5?Sp

6、herex?4?r?m?s?.?e?c?U?h?s?u?0?c?s?m?s?.?20%?c?c?f?:?H?e?g9?w?D?v?n?n?s?1?r?z?g83.1.4?4?T?e?t?i?0?e?c?s?U?c?5?5?c?vCO2?H2O?c?H?o?u?c?8?,?A?o?u?Hg8?v?4?o?a?c?H?s?u?4?o?,g8?10?:?n?v115.76?35.944?m,?p?37.16%?4,?s?u?r8h,?g21.55?12.184?g?g-1,?r?z?s?,?:?Y?3.16?0.044?g?g-1,?s?u?w?C?w?d?AUC?s?g8?-?s?u?4?s?g?

7、u?,?H?g83.1.5?4?T?-?.?O?,?:?U,?g9?v?U,?5?U?,?V?8?u?g9?:?Y?g8?V?11?4?s?u?f?)?H?g8?4?6?u?s?p?i?T?a,?w,?u?s?u?4?f?k?k?(?458000)?,?s?u?4?i?0?a?:?Y?c?,?s?i?4?g?0?c?k?v?w?g8?x?k?u?4?H?S?w?i?r?H?c?s?t?4?i?c?k?g8?,?s?u?4?S?w?TCAEHiguchi985985?+?+?k?d?ChineseMedicineModernDistanceEducationofChina?x6?x08?5200

8、8?08?e?s?v100?5004?m,?4?t?U?g8?v?H?:?t?0?4,?s?u?0?H?,?4?8?U?g8?x?o?)?s?v?Y?,?w?o?8?v?o?(?4?g83.1.6?4?v?.?w?s?:?wg9?5?H?c?v?:?Y?g8?s?e?H?c?H?w?+?u?u?c?v?U?k?w?c?f?H?t?i?c?P?w?w?c?U?w?u?t?c?v?w?u?Y?Hg8?12?H?0.f?T?A?:?n?4?5.fFU?4?c?0?g9?s?u?r?c?4?w?U?c?s?U?u?+?7?s?w?c?s?v?U?u?w?Hg8?v?v?F?0?5.fFU?s?U?H?

9、S?v?c?c?V?L?g83.2?5?s?u?4?5?s?u?4?u?r?9?c?s?v?U?u?Hg8?4?H?T?u?V?U?u?c?H?k?s?.?g83.2.1?.?4?.?T?g9?5?U?g9?u?e?t?i?,?O?5?U,?T?V?H?V?U?u?Y?c?H?g?5?u?g8?4?H?-?.?4?U?.?o?,?s?4?U?.?5?:?i?p?v?5?i?)g9?.?4?13.14g97.54?5.66?o?c?f?H?S?d?S?k?5?c?r?z?s?g83.2.2?4?0?f?s?V?U?u?,?w?U?o?D?s?u?Yg8?13?H?v50?1004?m?100?3

10、004?m?4,?20?s?u?,?u?r?o?c?w?.?r?w?u?p?s?L?,?L?4?,?o?c?d?4?9?o?5?0,?r?4?u?D?s,?g?V?u?g8g?g?0?c14?0?f?v?c?v?u?c?s?5?U?c?c?9?u?w?c?p?s?w?g?s?u?Hg84?g?g?s?u?4?v?Y?c?s?u?T?a?U?4?u?U?e?H?c?)?u?g9?k?v?w?l?w?c?c?v?g?4?a?U?c?H?)?M?s?o?g?g8?w?f?,?c?4?u?r?5?u?s?o?c?g8?John?15?H?4?u?S?h?+?c?14%?g?g8?T?v?s?4?k?e

11、?T?s?c?w?N?a?c?g8g?g?s?s?u?4?f?,?c?U?i?+?f?M?c?5?H?)?M?8?g8?v?s?u?T?H?U?D?c?r?k?e?L?T?s?U?g8?0?c?O?D?c?u?4?4?,?4?C?i?0?U?0?c?w?4?4?i?4g9?6g8?4?U?D?y?u?s?w?g8?L?U?c?p?s?u?c?t?g8?L?D?,?,?s?k?e?T?s?c?S?T?S?w?o?Y?c?s?w?g9?.f?s?c?u?4?D?c?u?,?.f?s?g9?.f?s?g9?w?g?s?w?c?D?u?c?7?g8?0?c?u?4?8?c?8?D?s?5?i?g8?O

12、?Y?h?o?y?:?n?c?:?Y?)?c?s?u?4?)?H?Ug8?4?1?C?e?,?F?.?T?u?Y?:?nJ.?+?k?,?Y?,2003,34(8):391-392.2?)?,?,?a.?,?5?-?Y?s?u?U?.?f?J.?+?k?,?Y?,1999,30(4):162-165.3?O?.?Y?M.?x?,?2?:?0?,?z,2003:471.4?.?s?u?4?v?f?J.?+?k?,?Y?,1990,21(10):472-477.5PathiRamon,VoyvodicFrank.Spontaneousextraperitonealhaemorrhage:compu

13、tedtomographydiagnosisandtreatmentbyselectivearterialembolizationJ.AustralasianRadiology,2004,48(2):123-128.6?.?m?s?.?s?u?r?4?f?J.?k?U?,1997,14(3):49-517?d?,?,?0?,?.?0?s?u?0?H?5?K?U?4?f?:J.?+?Y?,1993,28(8):479-481.8?%,?4?,?0?,?.?.f?4?s?u?f?J.?,2001,13(1):23-25.9TaguchiT.Livertumortargetingofdrugs:Sp

14、herex,avascularocclusiveagentJ.GanToKagakuRyoho,1995,22(7):969.10?,?a?l,?.?.?4?z?U?s?u?f?J.?,1993,28(10):792.11?,?,?V?.?4?s?u?0?)?f?J.?2?k?U?,1995,27(5):381.12?,?5,?.?.?5?K?U?4?U?h?s?u?r?J.?+?k?Y?,2001,21(11):643.13?,?,?.?PVA?4?s?u?f?J.?+?z?C?Y?,1989,23(6):330.14KuboM,KuwayamaN,HirashimaY,etal.Hydro

15、xyapatiteceramicsasaparticulateembolicmaterial:reportofthephysicalpropertiesofthehydroxyapatiteparticlesandtheanimalstudyJ.AJNRAmJNeuroradiol,2003,24(8):1540-154415JohnFPayne,StanleyJRobboy,AFHaney.EmbolicmicrisphereswithinovarianarterialvasculatureafteruterinearteryembolizationJ.obstetricsgynecology,2002,100(5):PART1,883-886.16?s.?:?Y?TM.?x?.?2?:?0?,?z,2004:128.(?:?K?5?,5?s12008-0-20

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